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BRIAN SPAR, M.D.
M.D.
Internal Medicine Physician
NPI: 1528062916Individual
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
MD022298E(PA)
Nephrology Physician
Internal Medicine — Nephrology
Code: 207RN0300X
MD022298E(PA)
Research & Publications (14)
Synthesis of novel bicyclo[4.1.0]heptane and bicyclo[3.1.0]hexane derivatives as melanin-concentrating hormone receptor R1 antagonists.
PMID 17604169·Bioorg Med Chem Lett·2007
7-preclinical
SAR study of bicyclo[4.1.0]heptanes as melanin-concentrating hormone receptor R1 antagonists: taming hERG.
PMID 17572094·Bioorg Med Chem·2007
7-preclinical
Novel aminobenzimidazoles as selective MCH-R1 antagonists for the treatment of metabolic diseases.
PMID 16889961·Bioorg Med Chem Lett·2006
7-preclinical
Design and synthesis of orally efficacious benzimidazoles as melanin-concentrating hormone receptor 1 antagonists.
PMID 16690315·Bioorg Med Chem Lett·2006
7-preclinical
Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas.
PMID 16570926·J Med Chem·2006
7-preclinical
Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice.
PMID 16540104·Eur J Pharmacol·2006
7-preclinical
Bicyclic[4.1.0]heptanes as phenyl replacements for melanin concentrating hormone receptor antagonists.
PMID 16442800·Bioorg Med Chem·2006
7-preclinical
Biaryl ureas as potent and orally efficacious melanin concentrating hormone receptor 1 antagonists for the treatment of obesity.
PMID 16033253·J Med Chem·2005
7-preclinical
Transgenic overexpression of neuromedin U promotes leanness and hypophagia in mice.
PMID 15817836·J Endocrinol·2005
7-preclinical
Discovery of bicycloalkyl urea melanin concentrating hormone receptor antagonists: orally efficacious antiobesity therapeutics.
PMID 15801820·J Med Chem·2005
7-preclinical
Melanin-concentrating hormone-1 receptor antagonism decreases feeding by reducing meal size.
PMID 15321733·Eur J Pharmacol·2004
4-observational
Meal pattern analysis of diet-induced obesity in susceptible and resistant rats.
PMID 12855753·Obes Res·2003
7-preclinical
A role for the melanocortin 4 receptor in sexual function.
PMID 12172010·Proc Natl Acad Sci U S A·2002
7-preclinical
Photoperiodic regulation of the reproductive axis in male zebra finches, Taeniopygia guttata.
PMID 10764555·Gen Comp Endocrinol·2000
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 475 N WEABER ST
ANNVILLE, PA 17003 - Phone
- (717) 867-4671
Quick Facts
- NPI
- 1528062916
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 1
- Publications
- 14
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