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NORMAN SHARPLESS, MD
MD
Hematology & Oncology Physician
NPI: 1528129681Individual
Specialties, Licenses & Credentials
Hematology & Oncology PhysicianPrimary
Internal Medicine — Hematology & Oncology
Code: 207RH0003X
Research & Publications (20)
The mighty mouse: genetically engineered mouse models in cancer drug development.
PMID 16915232·Nat Rev Drug Discov·2006
6-review
The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.
PMID 14724566·Oncogene·2004
7-preclinical
Both products of the mouse Ink4a/Arf locus suppress melanoma formation in vivo.
PMID 12902988·Oncogene·2003
7-preclinical
Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.
PMID 11779495·Mol Cell·2001
7-preclinical
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.
PMID 11544531·Nature·2001
7-preclinical
p38MAPK controls expression of multiple cell cycle inhibitors and islet proliferation with advancing age.
PMID 19619499·Dev Cell·2009
7-preclinical
INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis.
PMID 19343170·PLoS One·2009
8-other
Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging.
PMID 19485966·Aging Cell·2009
8-other
HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice.
PMID 19662677·J Clin Invest·2009
7-preclinical
Decreased IRF8 expression found in aging hematopoietic progenitor/stem cells.
PMID 18596738·Leukemia·2009
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 101 MANNING DR
CHAPEL HILL, NC 27599 - Phone
- (919) 966-4996
Quick Facts
- NPI
- 1528129681
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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