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JEFFREY ENGELMAN, MD PHD
MD PHD
Internal Medicine Physician
NPI: 1538159108Individual
Specialties, Licenses & Credentials
Research & Publications (20)
Targeting PI3K signalling in cancer: opportunities, challenges and limitations.
PMID 19629070·Nat Rev Cancer·2009
6-review
Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer.
PMID 18483355·Clin Cancer Res·2008
6-review
PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib.
PMID 18089823·Cancer Res·2007
7-preclinical
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling.
PMID 17463250·Science·2007
7-preclinical
The role of the ErbB family members in non-small cell lung cancers sensitive to epidermal growth factor receptor kinase inhibitors.
PMID 16857813·Clin Cancer Res·2006
6-review
Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer.
PMID 16906227·J Clin Invest·2006
7-preclinical
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism.
PMID 16847462·Nat Rev Genet·2006
6-review
ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines.
PMID 15731348·Proc Natl Acad Sci U S A·2005
7-preclinical
Factors predicting response to EGFR tyrosine kinase inhibitors.
PMID 16052433·Semin Respir Crit Care Med·2005
6-review
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
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Contact & Hours
- Address
- 55 FRUIT ST, YAWKEY 10B
BOSTON, MA 02114 - Phone
- (617) 724-4000
Quick Facts
- NPI
- 1538159108
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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