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SMITA RAMANADHAM, MD

MD

Plastic Surgery Physician

NPI: 1548464324Individual

Specialties, Licenses & Credentials

Surgery Physician

Surgery

Code: 208600000X

260824(MA)
Plastic and Reconstructive Surgery Physician

Surgery — Plastic and Reconstructive Surgery

Code: 2086S0122X

260824(MA)
Plastic Surgery PhysicianPrimary

Plastic Surgery

Code: 208200000X

260824(MA)

Research & Publications (20)

Protease inhibitors used in the treatment of HIV+ induce beta-cell apoptosis via the mitochondrial pathway and compromise insulin secretion.
PMID 19208856·Am J Physiol Endocrinol Metab·2009
7-preclinical
Skeletal muscle group VIA phospholipase A2 (iPLA2beta): expression and role in fatty acid oxidation.
PMID 18937505·Biochemistry·2008
7-preclinical
Calcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis.
PMID 18936091·J Biol Chem·2008
7-preclinical
Age-related changes in bone morphology are accelerated in group VIA phospholipase A2 (iPLA2beta)-null mice.
PMID 18349124·Am J Pathol·2008
7-preclinical
HIV-protease inhibitors induce expression of suppressor of cytokine signaling-1 in insulin-sensitive tissues and promote insulin resistance and type 2 diabetes mellitus.
PMID 18171911·Am J Physiol Endocrinol Metab·2008
7-preclinical
Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2.
PMID 17627946·J Biol Chem·2007
7-preclinical
The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase.
PMID 17685585·Biochemistry·2007
8-other
Insulin secretory responses and phospholipid composition of pancreatic islets from mice that do not express Group VIA phospholipase A2 and effects of metabolic stress on glucose homeostasis.
PMID 16732058·J Biol Chem·2006
7-preclinical
Effects of biological oxidants on the catalytic activity and structure of group VIA phospholipase A2.
PMID 16700550·Biochemistry·2006
7-preclinical
A bromoenol lactone suicide substrate inactivates group VIA phospholipase A2 by generating a diffusible bromomethyl keto acid that alkylates cysteine thiols.
PMID 16411783·Biochemistry·2006
8-other
Effects of stable suppression of Group VIA phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells.
PMID 16286468·J Biol Chem·2006
7-preclinical
Group VIA phospholipase A2 forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIbeta expressed in pancreatic islet beta-cells.
PMID 15576376·J Biol Chem·2005
7-preclinical
The expression and function of a group VIA calcium-independent phospholipase A2 (iPLA2beta) in beta-cells.
PMID 15573142·Can J Physiol Pharmacol·2004
6-review
Characterization of N-terminal processing of group VIA phospholipase A2 and of potential cleavage sites of amyloid precursor protein constructs by automated identification of signature peptides in LC/MS/MS analyses of proteolytic digests.
PMID 15589755·J Am Soc Mass Spectrom·2004
7-preclinical
Male mice that do not express group VIA phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility.
PMID 15252026·J Biol Chem·2004
7-preclinical
Beta-cell calcium-independent group VIA phospholipase A(2) (iPLA(2)beta): tracking iPLA(2)beta movements in response to stimulation with insulin secretagogues in INS-1 cells.
PMID 14749286·Diabetes·2004
8-other
Islet complex lipids: involvement in the actions of group VIA calcium-independent phospholipase A(2) in beta-cells.
PMID 14749285·Diabetes·2004
6-review
Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta.
PMID 14744135·Biochemistry·2004
7-preclinical
Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript.
PMID 14636061·Biochemistry·2003
7-preclinical
Delta6-, Stearoyl CoA-, and Delta5-desaturase enzymes are expressed in beta-cells and are altered by increases in exogenous PUFA concentrations.
PMID 11923099·Biochim Biophys Acta·2002
7-preclinical

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

Contact & Hours

Address
2 CORNWALL DRIVE, UNIT B2
EAST BRUNSWICK, NJ 08816

Location

Practice Location

2 CORNWALL DRIVE, EAST BRUNSWICK, NJ
(617) 233-9928

Quick Facts

NPI
1548464324
Entity Type
Individual
Gender
Female
Medicare
Not confirmed
Specialties
3
Locations
1
Publications
20

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