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TIMOTHY SOWIN, MD

MD

Psychiatry Physician

NPI: 1568441509Individual

Specialties, Licenses & Credentials

Aerospace Medicine Physician

Preventive Medicine — Aerospace Medicine

Code: 2083A0100X

162633-1(NY)
Psychiatry PhysicianPrimary

Psychiatry & Neurology — Psychiatry

Code: 2084P0800X

162633(NY)

Research & Publications (20)

Major depressive disorder in military aviators: a retrospective study of prevalence.
PMID 19653579·Aviat Space Environ Med·2009
8-other
Isoxazolo[3,4-b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular modeling.
PMID 18790640·Bioorg Med Chem Lett·2008
8-other
Cyclin B1 is an efficacy-predicting biomarker for Chk1 inhibitors.
PMID 18671143·Biomarkers·2008
7-preclinical
Investigation of novel 7,8-disubstituted-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-ones as potent Chk1 inhibitors.
PMID 18358720·Bioorg Med Chem Lett·2008
8-other
Macrocyclic ureas as potent and selective Chk1 inhibitors: an improved synthesis, kinome profiling, structure-activity relationships, and preliminary pharmacokinetics.
PMID 17935989·Bioorg Med Chem Lett·2007
4-observational
Synthesis and in-vitro biological activity of macrocyclic urea Chk1 inhibitors.
PMID 17931867·Bioorg Med Chem Lett·2007
4-observational
Discovery of 4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzonitriles and 4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-pyridine-2'-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors.
PMID 17827013·Bioorg Med Chem Lett·2007
8-other
Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: improving oral biovailability.
PMID 17768051·Bioorg Med Chem Lett·2007
7-preclinical
Design, synthesis, and biological activity of 5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one-based potent and selective Chk-1 inhibitors.
PMID 17658776·J Med Chem·2007
7-preclinical
Synthesis and biological evaluation of 4'-(6,7-disubstituted-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-biphenyl-4-ol as potent Chk1 inhibitors.
PMID 17544271·Bioorg Med Chem Lett·2007
8-other
1,4-Dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: extended exploration on phenyl ring substitutions and preliminary ADME/PK studies.
PMID 17490879·Bioorg Med Chem Lett·2007
7-preclinical
1,4-Dihydroindeno[1,2-c]pyrazoles with acetylenic side chains as novel and potent multitargeted receptor tyrosine kinase inhibitors with low affinity for the hERG ion channel.
PMID 17425296·J Med Chem·2007
7-preclinical
Synthesis and biological evaluation of 5-substituted 1,4-dihydroindeno[1,2-c]pyrazoles as multitargeted receptor tyrosine kinase inhibitors.
PMID 17391959·Bioorg Med Chem Lett·2007
7-preclinical
Structure-based design, synthesis, and biological evaluation of potent and selective macrocyclic checkpoint kinase 1 inhibitors.
PMID 17352464·J Med Chem·2007
8-other
Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors.
PMID 17287122·Bioorg Med Chem·2007
8-other
Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics.
PMID 17019715·Int J Cancer·2006
8-other
Kinase drug discovery by affinity selection/mass spectrometry (ASMS): application to DNA damage checkpoint kinase Chk1.
PMID 16956998·J Biomol Screen·2006
8-other
Differential roles of checkpoint kinase 1, checkpoint kinase 2, and mitogen-activated protein kinase-activated protein kinase 2 in mediating DNA damage-induced cell cycle arrest: implications for cancer therapy.
PMID 16928813·Mol Cancer Ther·2006
8-other
1,4-Dihydroindeno[1,2-c]pyrazoles as novel multitargeted receptor tyrosine kinase inhibitors.
PMID 16759855·Bioorg Med Chem Lett·2006
8-other
Hit-to-lead optimization of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of KDR kinase inhibitors.
PMID 16750628·Bioorg Med Chem Lett·2006
7-preclinical

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

Contact & Hours

Address
1100 WILFORD HALL LOOP BLDG 4554
JBSA LACKLAND, TX 78236

Location

Practice Location

1100 WILFORD HALL LOOP BLDG 4554, JBSA LACKLAND, TX
(210) 292-7361

Quick Facts

NPI
1568441509
Entity Type
Individual
Gender
Male
Medicare
Not confirmed
Specialties
2
Locations
1
Publications
20

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