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ANN WYTTENBACH, MD
MD
Family Medicine Physician
NPI: 1578616918Individual
Specialties, Licenses & Credentials
Family Medicine PhysicianPrimary
Family Medicine
Code: 207Q00000X
9600376(NC)
Research & Publications (20)
Amelioration of protein misfolding disease by rapamycin: translation or autophagy?
PMID 18418060·Autophagy·2008
7-preclinical
Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons.
PMID 19268537·Neurobiol Dis·2009
7-preclinical
Differential phosphoprotein labelling (DIPPL) using 32P and 33P.
PMID 19241002·Methods Mol Biol·2009
6-review
Cytoplasmic inclusions of Htt exon1 containing an expanded polyglutamine tract suppress execution of apoptosis in sympathetic neurons.
PMID 19118173·J Neurosci·2008
7-preclinical
Polyglutamine gene function and dysfunction in the ageing brain.
PMID 18582603·Biochim Biophys Acta·2008
6-review
Expression of the small heat shock protein family in the mouse CNS: differential anatomical and biochemical compartmentalization.
PMID 18384969·Neuroscience·2008
7-preclinical
Rapamycin inhibits polyglutamine aggregation independently of autophagy by reducing protein synthesis.
PMID 18199701·Mol Pharmacol·2008
7-preclinical
Time-lapse analysis of aggregate formation in an inducible PC12 cell model of Huntington's disease reveals time-dependent aggregate formation that transiently delays cell death.
PMID 18158109·Brain Res Bull·2008
7-preclinical
Huntingtin inclusion bodies are iron-dependent centers of oxidative events.
PMID 17116244·FEBS J·2006
7-preclinical
Analysis of oxidative events induced by expanded polyglutamine huntingtin exon 1 that are differentially restored by expression of heat shock proteins or treatment with an antioxidant.
PMID 16817855·FEBS J·2006
7-preclinical
The BH3-only protein Puma is both necessary and sufficient for neuronal apoptosis induced by DNA damage in sympathetic neurons.
PMID 16478523·J Neurochem·2006
4-observational
Differential phosphoprotein labeling (DIPPL), a method for comparing live cell phosphoproteomes using simultaneous analysis of (33)P- and (32)P-labeled proteins.
PMID 16301211·Mol Cell Proteomics·2006
4-observational
Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite.
PMID 16166651·Mol Cell Biol·2005
7-preclinical
Aggravation of necrotic death of glucose-deprived cells by the MEK1 inhibitors U0126 and PD184161 through depletion of ATP.
PMID 15194007·Biochem Pharmacol·2004
7-preclinical
Role of heat shock proteins during polyglutamine neurodegeneration: mechanisms and hypothesis.
PMID 15126694·J Mol Neurosci·2004
6-review
Expression of mutant huntingtin blocks exocytosis in PC12 cells by depletion of complexin II.
PMID 12807877·J Biol Chem·2003
7-preclinical
Modulation of polyglutamine-induced cell death by genes identified by expression profiling.
PMID 12217956·Hum Mol Genet·2002
7-preclinical
Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin.
PMID 11978772·Hum Mol Genet·2002
7-preclinical
Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease.
PMID 11532992·Hum Mol Genet·2001
7-preclinical
Wild type Huntingtin reduces the cellular toxicity of mutant Huntingtin in mammalian cell models of Huntington's disease.
PMID 11432963·J Med Genet·2001
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 901 JEFFERSON DR
CHARLOTTE, NC 28270 - Phone
- (704) 366-1215
Quick Facts
- NPI
- 1578616918
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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