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RAFAEL LEFKOWITZ, M.D.
M.D.
Internal Medicine Physician
NPI: 1578715033Individual
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
049579(CT)
Occupational Medicine Physician
Preventive Medicine — Occupational Medicine
Code: 2083X0100X
49579(CT)
Research & Publications (20)
New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors.
PMID 17157248·Mol Cell·2006
6-review
A phase II study of flavopiridol (Alvocidib) in combination with docetaxel in refractory, metastatic pancreatic cancer.
PMID 19451750·Pancreatology·2009
3-trial
Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL.
PMID 19584355·Sci Signal·2009
8-other
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands.
PMID 19497875·Proc Natl Acad Sci U S A·2009
8-other
Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2.
PMID 19363159·Proc Natl Acad Sci U S A·2009
7-preclinical
Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor.
PMID 19254952·J Biol Chem·2009
7-preclinical
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation.
PMID 19171933·J Biol Chem·2009
7-preclinical
Local changes in bone marrow at MRI after treatment of extremity soft tissue sarcoma.
PMID 18704399·Skeletal Radiol·2009
8-other
beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice.
PMID 19349687·J Clin Invest·2009
7-preclinical
Evaluating variability in tumor measurements from same-day repeat CT scans of patients with non-small cell lung cancer.
PMID 19561260·Radiology·2009
8-other
Beta-arrestin scaffolding of phosphatidylinositol 4-phosphate 5-kinase Ialpha promotes agonist-stimulated sequestration of the beta2-adrenergic receptor.
PMID 18534983·J Biol Chem·2008
7-preclinical
S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking.
PMID 18691971·Mol Cell·2008
7-preclinical
Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor.
PMID 18524885·Mol Pharmacol·2008
8-other
Beta-arrestin-mediated localization of smoothened to the primary cilium.
PMID 18497258·Science·2008
7-preclinical
Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration.
PMID 18519945·Circ Res·2008
7-preclinical
Urinary hepcidin excretion in patients with myelodysplastic syndrome and myelofibrosis.
PMID 18498424·Br J Haematol·2008
8-other
Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).
PMID 18662895·Clin Immunol·2008
7-preclinical
A phase 1 dose-escalation study of irinotecan in combination with 17-allylamino-17-demethoxygeldanamycin in patients with solid tumors.
PMID 18927314·Clin Cancer Res·2008
3-trial
Distinct conformational changes in beta-arrestin report biased agonism at seven-transmembrane receptors.
PMID 18621717·Proc Natl Acad Sci U S A·2008
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 20 YORK ST # T-209, YALE-NEW HAVEN HOSPITAL
NEW HAVEN, CT 06510 - Phone
- (203) 688-2259
Quick Facts
- NPI
- 1578715033
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 1
- Publications
- 20
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