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ROBERT COFFMAN, DO, MS
DO, MS
Student in an Organized Health Care Education/Training Program
NPI: 1588458301Individual
Specialties, Licenses & Credentials
Student in an Organized Health Care Education/Training ProgramPrimary
Student in an Organized Health Care Education/Training Program
Code: 390200000X
Research & Publications (20)
Signalling pathways leading to IFN-alpha production in human plasmacytoid dendritic cell and the possible use of agonists or antagonists of TLR7 and TLR9 in clinical indications.
PMID 19093959·J Intern Med·2009
6-review
Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes. J. Exp. Med. 1989. 170: 1039-1044.
PMID 19109127·J Immunol·2009
7-preclinical
Biomarkers measuring the activity of Toll-like receptor ligands in clinical development programs.
PMID 19378019·Methods Mol Biol·2009
8-other
Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma.
PMID 19519691·Br J Haematol·2009
3-trial
Development of TLR inhibitors for the treatment of autoimmune diseases.
PMID 18613842·Immunol Rev·2008
6-review
CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans.
PMID 18765557·Clin Cancer Res·2008
3-trial
Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections.
PMID 18806803·Nat Med·2008
7-preclinical
PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation.
PMID 18227218·J Exp Med·2008
8-other
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists.
PMID 17479101·Nat Med·2007
6-review
Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms.
PMID 18034431·Eur J Immunol·2007
7-preclinical
Origins of the T(H)1-T(H)2 model: a personal perspective.
PMID 16715060·Nat Immunol·2006
7-preclinical
Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation.
PMID 16864658·J Exp Med·2006
8-other
Toll-like receptor recognition regulates immunodominance in an antimicrobial CD4+ T cell response.
PMID 17000122·Immunity·2006
7-preclinical
Severe community-acquired pneumonia due to Staphylococcus aureus, 2003-04 influenza season.
PMID 16707043·Emerg Infect Dis·2006
8-other
Immunostimulatory sequences regulate interferon-inducible genes but not allergic airway responses.
PMID 16574937·Am J Respir Crit Care Med·2006
4-observational
Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis.
PMID 17021320·N Engl J Med·2006
3-trial
Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation. 1982.
PMID 16034071·J Immunol·2005
7-preclinical
Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus.
PMID 16230478·J Exp Med·2005
4-observational
Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses.
PMID 16286015·Immunity·2005
8-other
Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction.
PMID 16314434·J Exp Med·2005
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 205 NORTH THIRD STREET, SECOND FLOOR
HARRISBURG, PA 17110 - Phone
- (717) 782-2100
Quick Facts
- NPI
- 1588458301
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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