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KATHLEEN M ANDRIES MD
MD
Internal Medicine Physician
NPI: 1588623276Individual
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
KA036485(MI)
Research & Publications (20)
Diarylquinolines are bactericidal for dormant mycobacteria as a result of disturbed ATP homeostasis.
PMID 18625705·J Biol Chem·2008
8-other
A once-weekly R207910-containing regimen exceeds activity of the standard daily regimen in murine tuberculosis.
PMID 18948422·Am J Respir Crit Care Med·2009
7-preclinical
Synthesis and biological evaluation of C-5 methyl substituted 4-arylthio and 4-aryloxy-3-Iodopyridin-2(1H)-one type anti-HIV agents.
PMID 19645483·J Med Chem·2009
8-other
Selectivity of TMC207 towards mycobacterial ATP synthase compared with that towards the eukaryotic homologue.
PMID 19075053·Antimicrob Agents Chemother·2009
4-observational
The diarylquinoline R207910 is bactericidal against Mycobacterium leprae in mice at low dose and administered intermittently.
PMID 19596891·Antimicrob Agents Chemother·2009
7-preclinical
Sterilizing activity of R207910 (TMC207)-containing regimens in the murine model of tuberculosis.
PMID 19590024·Am J Respir Crit Care Med·2009
7-preclinical
The diarylquinoline TMC207 for multidrug-resistant tuberculosis.
PMID 19494215·N Engl J Med·2009
3-trial
Prevention of drug carryover effects in studies assessing antimycobacterial efficacy of TMC207.
PMID 18480227·J Clin Microbiol·2008
7-preclinical
R75761, a lead compound for the development of antiviral drugs in late stage poliomyelitis eradication strategies and beyond.
PMID 18294707·Antiviral Res·2008
8-other
Impact of the interaction of R207910 with rifampin on the treatment of tuberculosis studied in the mouse model.
PMID 18644960·Antimicrob Agents Chemother·2008
7-preclinical
Potential use of antiviral agents in polio eradication.
PMID 18394270·Emerg Infect Dis·2008
4-observational
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate. 2. Discovery of a morpholinopropylaminobenzimidazole derivative (TMC353121).
PMID 18254606·J Med Chem·2008
7-preclinical
Diarylquinolines target subunit c of mycobacterial ATP synthase.
PMID 17496888·Nat Chem Biol·2007
8-other
Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910.
PMID 17517834·Antimicrob Agents Chemother·2007
7-preclinical
A dual chamber model of female cervical mucosa for the study of HIV transmission and for the evaluation of candidate HIV microbicides.
PMID 17097156·Antiviral Res·2007
8-other
A computational model of the inhibition of Mycobacterium tuberculosis ATPase by a new drug candidate R207910.
PMID 17387738·Proteins·2007
8-other
In vitro antimycobacterial spectrum of a diarylquinoline ATP synthase inhibitor.
PMID 17709466·Antimicrob Agents Chemother·2007
8-other
Structure-activity relationship in the 3-iodo-4-phenoxypyridinone (IOPY) series: The nature of the C-3 substituent on anti-HIV activity.
PMID 17157017·Bioorg Med Chem Lett·2007
8-other
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate, part 1: improving the pharmacokinetic profile using the structure-property relationship.
PMID 17722899·J Med Chem·2007
7-preclinical
Synergistic activity of R207910 combined with pyrazinamide against murine tuberculosis.
PMID 17178794·Antimicrob Agents Chemother·2007
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 4025 HEALTH PARK LN
SAINT JOSEPH, MI 49085 - Phone
- (269) 429-7100
Quick Facts
- NPI
- 1588623276
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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