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WILLIAM AHERNE, M.D.
M.D.
Ophthalmology Physician
NPI: 1609860766Individual
Specialties, Licenses & Credentials
Research & Publications (20)
Phase I pharmacokinetic and pharmacodynamic study of LAQ824, a hydroxamate histone deacetylase inhibitor with a heat shock protein-90 inhibitory profile, in patients with advanced solid tumors.
PMID 18927309·Clin Cancer Res·2008
3-trial
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis.
PMID 18413753·Cancer Res·2008
7-preclinical
Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of a novel histone deacetylase inhibitor, LAQ824, in human colon carcinoma cells and xenografts.
PMID 18392140·Neoplasia·2008
7-preclinical
4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer.
PMID 18020435·J Med Chem·2008
7-preclinical
A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.
PMID 17700519·Oncogene·2008
4-observational
Application of meso scale technology for the measurement of phosphoproteins in human tumor xenografts.
PMID 17638539·Assay Drug Dev Technol·2007
7-preclinical
Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues.
PMID 17431102·Mol Cancer Ther·2007
7-preclinical
Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin.
PMID 17409432·Cancer Res·2007
8-other
The phosphoinositide-specific phospholipase C inhibitor U73122 (1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione) spontaneously forms conjugates with common components of cell culture medium.
PMID 17403917·Drug Metab Dispos·2007
8-other
A duplexed phenotypic screen for the simultaneous detection of inhibitors of the molecular chaperone heat shock protein 90 and modulators of cellular acetylation.
PMID 17363504·Mol Cancer Ther·2007
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
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Contact & Hours
- Address
- 171 ASHLEY AVE
CHARLESTON, SC 29425 - Phone
- (843) 792-1414
Quick Facts
- NPI
- 1609860766
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 1
- Publications
- 20
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