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RANDY SPRAGUE, M.D.
M.D.
Clinical Pharmacology Physician
NPI: 1649283623Individual
Specialties, Licenses & Credentials
Internal Medicine Physician
Internal Medicine
Code: 207R00000X
R7946(MO)
Clinical Pharmacology PhysicianPrimary
Clinical Pharmacology
Code: 208U00000X
R7946(MO)
Research & Publications (20)
Prostacyclin analogs stimulate receptor-mediated cAMP synthesis and ATP release from rabbit and human erythrocytes.
PMID 18574748·Microcirculation·2008
7-preclinical
Reduced expression of G(i) in erythrocytes of humans with type 2 diabetes is associated with impairment of both cAMP generation and ATP release.
PMID 17130508·Diabetes·2006
8-other
Expression of the heterotrimeric G protein Gi and ATP release are impaired in erythrocytes of humans with diabetes mellitus.
PMID 17089891·Adv Exp Med Biol·2006
8-other
Rabbit erythrocytes possess adenylyl cyclase type II that is activated by the heterotrimeric G proteins Gs and Gi.
PMID 16415502·Pharmacol Rep·2005
7-preclinical
Extracellular ATP signaling in the rabbit lung: erythrocytes as determinants of vascular resistance.
PMID 12689860·Am J Physiol Heart Circ Physiol·2003
7-preclinical
The role of G protein beta subunits in the release of ATP from human erythrocytes.
PMID 12512701·J Physiol Pharmacol·2002
8-other
Impaired release of ATP from red blood cells of humans with primary pulmonary hypertension.
PMID 11393171·Exp Biol Med (Maywood)·2001
7-preclinical
Participation of cAMP in a signal-transduction pathway relating erythrocyte deformation to ATP release.
PMID 11546651·Am J Physiol Cell Physiol·2001
7-preclinical
Adaptive force control in grasping as a function of level of developmental disability.
PMID 19627429·J Intellect Disabil Res·2009
8-other
Insulin inhibits low oxygen-induced ATP release from human erythrocytes: implication for vascular control.
PMID 19412833·Microcirculation·2009
7-preclinical
Erythrocytes: oxygen sensors and modulators of vascular tone.
PMID 19364913·Physiology (Bethesda)·2009
6-review
Iloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humans.
PMID 19252089·Am J Physiol Heart Circ Physiol·2009
4-observational
Phosphodiesterase 3 is present in rabbit and human erythrocytes and its inhibition potentiates iloprost-induced increases in cAMP.
PMID 18586889·Am J Physiol Heart Circ Physiol·2008
7-preclinical
Tremor frequency profile as a function of level of mental retardation.
PMID 17559296·Am J Ment Retard·2007
8-other
Force-velocity and power-velocity relationships during maximal short-term rowing ergometry.
PMID 17277601·Med Sci Sports Exerc·2007
8-other
Cyclooxygenase (COX)-1 and COX-2 participate in 5,6-epoxyeicosatrienoic acid-induced contraction of rabbit intralobar pulmonary arteries.
PMID 17267581·J Pharmacol Exp Ther·2007
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 3660 VISTA AVE
SAINT LOUIS, MO 63110 - Phone
- (314) 577-6095
Quick Facts
- NPI
- 1649283623
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 1
- Publications
- 20
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