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RAQUEL BREKKEN, M.D.
M.D.
Pediatrics Physician
NPI: 1649462805Individual
Specialties, Licenses & Credentials
Pediatrics PhysicianPrimary
Pediatrics
Code: 208000000X
001652(GA)
Research & Publications (20)
Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.
PMID 19546236·Mol Cell Biol·2009
7-preclinical
Effect of chronic morphine on the dentate gyrus neurogenic microenvironment.
PMID 19356684·Neuroscience·2009
7-preclinical
K-Ras promotes angiogenesis mediated by immortalized human pancreatic epithelial cells through mitogen-activated protein kinase signaling pathways.
PMID 19509115·Mol Cancer Res·2009
8-other
The acellular fraction of stored platelets promotes tumor cell invasion.
PMID 18541268·J Surg Res·2009
7-preclinical
Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth.
PMID 19668192·Nat Med·2009
7-preclinical
Secreted protein acidic and rich in cysteine as a regulator of murine ovarian cancer growth and chemosensitivity.
PMID 18992864·Am J Obstet Gynecol·2009
7-preclinical
Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts.
PMID 19567820·Mol Cancer Ther·2009
7-preclinical
A peptoid antagonist of VEGF receptor 2 recognizes a 'hotspot' in the extracellular domain distinct from the hormone-binding site.
PMID 18501615·Bioorg Med Chem·2008
7-preclinical
Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice.
PMID 18519694·Cancer Res·2008
7-preclinical
The pharmacophore of a peptoid VEGF receptor 2 antagonist includes both side chain and main chain residues.
PMID 18653335·Bioorg Med Chem Lett·2008
8-other
Reduced strain in abdominal aortic aneurysms after endovascular repair.
PMID 18729552·J Endovasc Ther·2008
4-observational
Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis.
PMID 18974151·Cancer Res·2008
7-preclinical
The Adnectin CT-322 is a novel VEGF receptor 2 inhibitor that decreases tumor burden in an orthotopic mouse model of pancreatic cancer.
PMID 19038046·BMC Cancer·2008
7-preclinical
Forced expression of MMP9 rescues the loss of angiogenesis and abrogates metastasis of pancreatic tumors triggered by the absence of host SPARC.
PMID 18445772·Exp Biol Med (Maywood)·2008
7-preclinical
A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity.
PMID 18386897·J Am Chem Soc·2008
7-preclinical
Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells.
PMID 18922901·Cancer Res·2008
8-other
Angiogenic role of LYVE-1-positive macrophages in adipose tissue.
PMID 17272806·Circ Res·2007
4-observational
Anti-VEGF-A therapy reduces lymphatic vessel density and expression of VEGFR-3 in an orthotopic breast tumor model.
PMID 17597103·Int J Cancer·2007
7-preclinical
Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma.
PMID 17909053·Cancer Res·2007
7-preclinical
Progestin-dependent progression of human breast tumor xenografts: a novel model for evaluating antitumor therapeutics.
PMID 17942925·Cancer Res·2007
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 4700 WATERS AVE
SAVANNAH, GA 31404 - Phone
- (912) 350-8200
Quick Facts
- NPI
- 1649462805
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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