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KENNETH STUBBS, M.D.
M.D.
Internal Medicine Physician
NPI: 1659312585Individual
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
15220(LA)09681(MS)
Research & Publications (18)
A selective inhibitor Gal-PUGNAc of human lysosomal beta-hexosaminidases modulates levels of the ganglioside GM2 in neuroblastoma cells.
PMID 19130519·Angew Chem Int Ed Engl·2009
8-other
Inactivation of the glycoside hydrolase NagZ attenuates antipseudomonal beta-lactam resistance in Pseudomonas aeruginosa.
PMID 19273679·Antimicrob Agents Chemother·2009
8-other
Insight into a strategy for attenuating AmpC-mediated beta-lactam resistance: structural basis for selective inhibition of the glycoside hydrolase NagZ.
PMID 19499593·Protein Sci·2009
8-other
Synthesis of 2-amido, 2-amino, and 2-azido derivatives of the nitrogen analogue of the naturally occurring glycosidase inhibitor salacinol and their inhibitory activities against O-GlcNAcase and NagZ enzymes.
PMID 18358456·Carbohydr Res·2008
8-other
Synthesis and use of mechanism-based protein-profiling probes for retaining beta-D-glucosaminidases facilitate identification of Pseudomonas aeruginosa NagZ.
PMID 18067297·J Am Chem Soc·2008
8-other
The synthesis and biological evaluation of some carbocyclic analogues of PUGNAc.
PMID 18804755·Carbohydr Res·2008
8-other
A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo.
PMID 18587388·Nat Chem Biol·2008
7-preclinical
Structural and mechanistic insight into the basis of mucopolysaccharidosis IIIB.
PMID 18443291·Proc Natl Acad Sci U S A·2008
8-other
A 1-acetamido derivative of 6-epi-valienamine: an inhibitor of a diverse group of beta-N-acetylglucosaminidases.
PMID 17728868·Org Biomol Chem·2007
8-other
Small molecule inhibitors of a glycoside hydrolase attenuate inducible AmpC-mediated beta-lactam resistance.
PMID 17439950·J Biol Chem·2007
8-other
Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise.
PMID 17227027·J Am Chem Soc·2007
8-other
Functional proteomic profiling of glycan-processing enzymes.
PMID 17116479·Methods Enzymol·2006
8-other
Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity.
PMID 16565725·Nat Struct Mol Biol·2006
4-observational
Identification of Asp174 and Asp175 as the key catalytic residues of human O-GlcNAcase by functional analysis of site-directed mutants.
PMID 16533067·Biochemistry·2006
4-observational
A divergent synthesis of 2-acyl derivatives of PUGNAc yields selective inhibitors of O-GlcNAcase.
PMID 16493467·Org Biomol Chem·2006
8-other
A highly concise preparation of O-deacetylated arylthioglycosides of N-acetyl-D-glucosamine from 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-alpha-D-glucopyranosyl chloride and aryl thiols or disulfides.
PMID 16472788·Carbohydr Res·2006
8-other
O-GlcNAcase catalyzes cleavage of thioglycosides without general acid catalysis.
PMID 16332065·J Am Chem Soc·2005
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 46 SERGEANT PRENTISS DR., SUITE 300
NATCHEZ, MS 39120 - Phone
- (601) 446-2084
Quick Facts
- NPI
- 1659312585
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 1
- Publications
- 18
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