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ROBERT HEUCKEROTH, MD

MD

Pediatric Gastroenterology Physician

NPI: 1659398188Individual

Specialties, Licenses & Credentials

Pediatric Gastroenterology PhysicianPrimary

Pediatrics — Pediatric Gastroenterology

Code: 2080P0206X

104739(MO)MD449684(PA)

Research & Publications (20)

Getting to the guts of enteric nervous system development.
PMID 16720873·Development·2006
7-preclinical
Finding your way to the end: a tale of GDNF and endothelin-3.
PMID 14659083·Neuron·2003
6-review
Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies.
PMID 19412548·PLoS One·2009
7-preclinical
Retinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro.
PMID 18561907·Dev Biol·2008
7-preclinical
Protein kinase Czeta and glycogen synthase kinase-3beta control neuronal polarity in developing rodent enteric neurons, whereas SMAD specific E3 ubiquitin protein ligase 1 promotes neurite growth but does not influence polarity.
PMID 17728459·J Neurosci·2007
7-preclinical
Mice lacking sister chromatid cohesion protein PDS5B exhibit developmental abnormalities reminiscent of Cornelia de Lange syndrome.
PMID 17652350·Development·2007
7-preclinical
PAI-1 deficiency reduces liver fibrosis after bile duct ligation in mice through activation of tPA.
PMID 17561000·FEBS Lett·2007
7-preclinical
Tissue-type plasminogen activator deficiency exacerbates cholestatic liver injury in mice.
PMID 17538930·Hepatology·2007
7-preclinical
Reduced endothelin converting enzyme-1 and endothelin-3 mRNA in the developing bowel of male mice may increase expressivity and penetrance of Hirschsprung disease-like distal intestinal aganglionosis.
PMID 17131407·Dev Dyn·2007
7-preclinical
BMP signaling regulates murine enteric nervous system precursor migration, neurite fasciculation, and patterning via altered Ncam1 polysialic acid addition.
PMID 16952347·Dev Biol·2006
7-preclinical
Differential gene expression and functional analysis implicate novel mechanisms in enteric nervous system precursor migration and neuritogenesis.
PMID 16904662·Dev Biol·2006
7-preclinical
Transcriptional profiling after bile duct ligation identifies PAI-1 as a contributor to cholestatic injury in mice.
PMID 16250054·Hepatology·2005
7-preclinical
Enteric neuroblasts require the phosphatidylinositol 3-kinase/Akt/Forkhead pathway for GDNF-stimulated survival.
PMID 15866051·Mol Cell Neurosci·2005
7-preclinical
A human yeast artificial chromosome containing the multiple endocrine neoplasia type 2B Ret mutation does not induce medullary thyroid carcinoma but does support the growth of kidneys and partially rescues enteric nervous system development in Ret-deficient mice.
PMID 15632018·Am J Pathol·2005
7-preclinical
GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration.
PMID 15541311·Neuron·2004
7-preclinical
Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis.
PMID 15469971·Development·2004
7-preclinical
Neurturin signalling via GFRalpha2 is essential for innervation of glandular but not muscle targets of sacral parasympathetic ganglion neurons.
PMID 15019945·Mol Cell Neurosci·2004
7-preclinical
Neurturin-deficient mice develop dry eye and keratoconjunctivitis sicca.
PMID 14507865·Invest Ophthalmol Vis Sci·2003
7-preclinical
GDNF availability determines enteric neuron number by controlling precursor proliferation.
PMID 12668632·Development·2003
7-preclinical
Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons.
PMID 12160745·Neuron·2002
7-preclinical

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

Contact & Hours

Address
3401 CIVIC CENTER BLVD, CHILDREN'S HOSPITAL OF PHILA - GASTRO & NUTRITION
PHILADELPHIA, PA 19104

Location

Practice Location

3401 CIVIC CENTER BLVD, PHILADELPHIA, PA
(215) 590-3247

Quick Facts

NPI
1659398188
Entity Type
Individual
Gender
Male
Medicare
Not confirmed
Specialties
2
Locations
1
Publications
20

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