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DAVID KIRN, M.D.
M.D.
Plastic Surgery Physician
NPI: 1659484681Individual
Specialties, Licenses & Credentials
Plastic Surgery PhysicianPrimary
Plastic Surgery
Code: 208200000X
29775(KY)
Research & Publications (20)
Oncolytic and immunostimulatory efficacy of a targeted oncolytic poxvirus expressing human GM-CSF following intravenous administration in a rabbit tumor model.
PMID 19629143·Cancer Gene Ther·2010
7-preclinical
Erythema elevatum diutinum as a paraneoplastic syndrome in a patient with pulmonary lymphoepithelioma-like carcinoma.
PMID 18571759·Lung Cancer·2009
5-case
Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer.
PMID 19104515·Nat Rev Cancer·2009
6-review
Targeted genetic and viral therapy for advanced head and neck cancers.
PMID 19508919·Drug Discov Today·2009
6-review
Enhancing poxvirus oncolytic effects through increased spread and immune evasion.
PMID 18381410·Cancer Res·2008
7-preclinical
Randomized phase 3 trial of interferon gamma-1b plus standard carboplatin/paclitaxel versus carboplatin/paclitaxel alone for first-line treatment of advanced ovarian and primary peritoneal carcinomas: results from a prospectively designed analysis of progression-free survival.
PMID 18314182·Gynecol Oncol·2008
3-trial
The targeted oncolytic poxvirus JX-594 demonstrates antitumoral, antivascular, and anti-HBV activities in patients with hepatocellular carcinoma.
PMID 18628758·Mol Ther·2008
8-other
E1A-expressing adenoviral E3B mutants act synergistically with chemotherapeutics in immunocompetent tumor models.
PMID 18034197·Cancer Gene Ther·2008
7-preclinical
Development of targeted oncolytic virotherapeutics through translational research.
PMID 18694356·Expert Opin Biol Ther·2008
6-review
Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial.
PMID 18495536·Lancet Oncol·2008
3-trial
Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis.
PMID 18815361·Proc Natl Acad Sci U S A·2008
7-preclinical
Translation of targeted oncolytic virotherapeutics from the lab into the clinic, and back again: a high-value iterative loop.
PMID 18500240·Mol Ther·2008
7-preclinical
Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus.
PMID 18162040·PLoS Med·2007
7-preclinical
Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963.
PMID 17965776·J Clin Invest·2007
7-preclinical
Targeting the untargetable: oncolytic virotherapy for the cancer stem cell.
PMID 18026182·Mol Ther·2007
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 2376 ALEXANDRIA DR
LEXINGTON, KY 40504 - Phone
- (859) 296-3195
Quick Facts
- NPI
- 1659484681
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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