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REBECCA LOBELL, M.D.
M.D.
Obstetrics & Gynecology Physician
NPI: 1659692382IndividualAccepts Medicare
Specialties, Licenses & Credentials
Obstetrics & Gynecology PhysicianPrimary
Obstetrics & Gynecology
Code: 207V00000X
53832(CO)
CMS Specialties
PrimaryOBSTETRICS/GYNECOLOGY
Education
UNIVERSITY OF KANSAS SCHOOL OF MED (KC/WICH/SAL)
Class of 2010
Research & Publications (20)
Development of thioquinazolinones, allosteric Chk1 kinase inhibitors.
PMID 19155174·Bioorg Med Chem Lett·2009
8-other
Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancer.
PMID 18578472·J Med Chem·2008
8-other
Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinase.
PMID 17900896·Bioorg Med Chem Lett·2007
8-other
Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP.
PMID 17804233·Bioorg Med Chem Lett·2007
7-preclinical
Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors.
PMID 17804227·Bioorg Med Chem Lett·2007
8-other
Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP.
PMID 17766111·Bioorg Med Chem Lett·2007
8-other
Kinesin spindle protein (KSP) inhibitors. Part 6: Design and synthesis of 3,5-diaryl-4,5-dihydropyrazole amides as potent inhibitors of the mitotic kinesin KSP.
PMID 17761419·Bioorg Med Chem Lett·2007
8-other
Kinesin spindle protein (KSP) inhibitors. Part V: discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by beta-fluorination to overcome cellular efflux by P-glycoprotein.
PMID 17395460·Bioorg Med Chem Lett·2007
8-other
An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis.
PMID 17101792·Mol Cell Biol·2007
8-other
Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors.
PMID 16990002·Bioorg Med Chem Lett·2006
7-preclinical
3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6.
PMID 16978863·Bioorg Med Chem Lett·2006
8-other
Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP.
PMID 16603356·Bioorg Med Chem Lett·2006
7-preclinical
Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP.
PMID 16439123·Bioorg Med Chem Lett·2006
8-other
Kinesin spindle protein (KSP) inhibitors. Part 3: synthesis and evaluation of phenolic 2,4-diaryl-2,5-dihydropyrroles with reduced hERG binding and employment of a phosphate prodrug strategy for aqueous solubility.
PMID 16439122·Bioorg Med Chem Lett·2006
7-preclinical
Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage.
PMID 16023598·Cancer Cell·2005
8-other
Macrocyclic piperazinones as potent dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I.
PMID 14741259·Bioorg Med Chem Lett·2004
8-other
A cell-based radioligand binding assay for farnesyl: protein transferase inhibitors.
PMID 14567795·J Biomol Screen·2003
7-preclinical
Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents.
PMID 12825937·J Med Chem·2003
7-preclinical
Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I.
PMID 12479371·Mol Cancer Ther·2002
7-preclinical
The synthesis and biological evaluation of a series of potent dual inhibitors of farnesyl and geranyl-Geranyl protein transferases.
PMID 12113834·Bioorg Med Chem Lett·2002
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via 2737 NE McBaine Dr · 2 locations total
- Address
- 2737 NE MCBAINE DR
LEES SUMMIT, MO 64064 - Phone
- (816) 251-5780
Quick Facts
- NPI
- 1659692382
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 2
- Years in Practice
- 16
- Publications
- 20
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