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BRUCE SACHAIS, MD
MD
Anatomic Pathology & Clinical Pathology Physician
NPI: 1669417747Individual
Specialties, Licenses & Credentials
Anatomic Pathology & Clinical Pathology PhysicianPrimary
Pathology — Anatomic Pathology & Clinical Pathology
Code: 207ZP0102X
MD067572L(PA)
Research & Publications (20)
Elimination of platelet factor 4 (PF4) from platelets reduces atherosclerosis in C57Bl/6 and apoE-/- mice.
PMID 18000617·Thromb Haemost·2007
7-preclinical
Long-term effects of LDL apheresis in patients with severe hypercholesterolemia.
PMID 15880364·J Clin Apher·2005
8-other
Interactions of platelet factor 4 with the vessel wall.
PMID 15282658·Semin Thromb Hemost·2004
6-review
Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic machinery, resulting in retention of low-density lipoprotein on the cell surface.
PMID 11986215·Blood·2002
7-preclinical
Platelet-endothelial interactions in atherosclerosis.
PMID 11487452·Curr Atheroscler Rep·2001
6-review
The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow.
PMID 17540842·Blood·2007
8-other
Heparin-induced thrombocytopenia: an autoimmune disorder regulated through dynamic autoantigen assembly/disassembly.
PMID 17285619·J Clin Apher·2007
6-review
Prothrombotic factors enhance heparin-induced thrombocytopenia and thrombosis in vivo in a mouse model.
PMID 16961586·J Thromb Haemost·2006
7-preclinical
Endothelial expression of E-selectin is induced by the platelet-specific chemokine platelet factor 4 through LRP in an NF-kappaB-dependent manner.
PMID 15591119·Blood·2005
8-other
Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia.
PMID 15304392·Blood·2005
7-preclinical
Platelet factor 4 localization in carotid atherosclerotic plaques: correlation with clinical parameters.
PMID 14652645·Thromb Haemost·2003
8-other
Factor VIII ectopically expressed in platelets: efficacy in hemophilia A treatment.
PMID 12881300·Blood·2003
7-preclinical
Antithrombotic thrombocytes: ectopic expression of urokinase-type plasminogen activator in platelets.
PMID 12689937·Blood·2003
7-preclinical
Platelet factor 4 enhances the binding of oxidized low-density lipoprotein to vascular wall cells.
PMID 12466273·J Biol Chem·2003
7-preclinical
Use of plasma exchange, steroids, and anticoagulation in a patient with multiple arterial thromboses and IgM anticardiolipin antibodies.
PMID 12378550·J Clin Apher·2002
5-case
Defining a second epitope for heparin-induced thrombocytopenia/thrombosis antibodies using KKO, a murine HIT-like monoclonal antibody.
PMID 11830470·Blood·2002
7-preclinical
Comparative costs of treating adults and children within selected diagnosis-related groups.
PMID 11751550·Clin Chem·2002
4-observational
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 3400 SPRUCE ST
PHILADELPHIA, PA 19104 - Phone
- (215) 662-6503
Quick Facts
- NPI
- 1669417747
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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