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DOUGLAS BRENNEMAN, D.O.
D.O.
Family Medicine Physician
NPI: 1669468831IndividualAccepts Medicare
Specialties, Licenses & Credentials
Family Medicine PhysicianPrimary
Family Medicine
Code: 207Q00000X
OS012261(PA)
CMS Specialties
PrimaryFAMILY PRACTICE
Education
PHILADELPHIA COLLEGE OF OSTEOPATHIC MEDICINE
Class of 2001
Research & Publications (20)
Neuroprotection: a comparative view of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide.
PMID 17513014·Peptides·2007
6-review
Cathepsins B and L differentially regulate amyloid precursor protein processing.
PMID 19064719·J Pharmacol Exp Ther·2009
7-preclinical
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
PMID 19388676·J Med Chem·2009
7-preclinical
Carisbamate, a novel neuromodulator, inhibits voltage-gated sodium channels and action potential firing of rat hippocampal neurons.
PMID 19013768·Epilepsy Res·2009
7-preclinical
A comparative analysis of brain and plasma Abeta levels in eight common non-transgenic mouse strains: validation of a specific immunoassay for total rodent Abeta.
PMID 17627487·Curr Alzheimer Res·2007
4-observational
Reduction of dominant or submissive behaviors as models for antimanic or antidepressant drug testing: technical considerations.
PMID 17645948·J Neurosci Methods·2007
4-observational
Assessing activity onset time and efficacy for clinically effective antidepressant and antimanic drugs in animal models based on dominant-submissive relationships.
PMID 17597209·Neurosci Biobehav Rev·2007
6-review
2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead.
PMID 17685503·J Med Chem·2007
7-preclinical
NAP and ADNF-9 protect normal and Down's syndrome cortical neurons from oxidative damage and apoptosis.
PMID 17430172·Curr Pharm Des·2007
4-observational
Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse.
PMID 17403913·Drug Metab Dispos·2007
7-preclinical
Levels of mRNA coding for alpha-, beta-, and gamma-synuclein in the brains of newborn, juvenile, and adult rats.
PMID 17085784·J Mol Neurosci·2006
4-observational
Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease.
PMID 17011205·Neurobiol Dis·2006
4-observational
Neonatal mice of the Down syndrome model, Ts65Dn, exhibit upregulated VIP measures and reduced responsiveness of cortical astrocytes to VIP stimulation.
PMID 17401158·J Mol Neurosci·2006
7-preclinical
In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice.
PMID 16815960·Drug Metab Dispos·2006
7-preclinical
The expression of activity-dependent neuroprotective protein (ADNP) is regulated by brain damage and treatment of mice with the ADNP derived peptide, NAP, reduces the severity of traumatic head injury.
PMID 15974912·Curr Alzheimer Res·2005
4-observational
Novel peptides prevent alcohol-induced spatial learning deficits and proinflammatory cytokine release in a mouse model of fetal alcohol syndrome.
PMID 16150281·Am J Obstet Gynecol·2005
7-preclinical
Reduction of Submissive Behavior Model for antidepressant drug activity testing: study using a video-tracking system.
PMID 16286818·Behav Pharmacol·2005
7-preclinical
8-(Heteroaryl)phenalkyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-ones as opioid receptor modulators.
PMID 16787343·Med Chem·2005
7-preclinical
Activity-dependent neurotrophic factor-9 and NAP promote neurite outgrowth in rat hippocampal and cortical cultures.
PMID 15800376·J Mol Neurosci·2005
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 2500 DELTA RD
BROGUE, PA 17309 - Phone
- (717) 927-8434
Quick Facts
- NPI
- 1669468831
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 25
- Publications
- 20
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