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GEORGE COSTANTINO, M.D.
M.D.
Surgery Physician
NPI: 1669496642Individual
Specialties, Licenses & Credentials
Surgery PhysicianPrimary
Surgery
Code: 208600000X
MD020986E(PA)
Research & Publications (20)
New promises for manipulation of kynurenine pathway in cancer and neurological diseases.
PMID 19236242·Expert Opin Ther Targets·2009
6-review
Treatment of life-threatening type I refractory coeliac disease with long-term infliximab.
PMID 17382609·Dig Liver Dis·2008
5-case
In silico approaches towards the understanding of the structure-function relationships in metabotropic glutamate receptors (mGluRs) and other family C GPRCs.
PMID 16796561·Curr Pharm Des·2006
6-review
Molecular dynamics simulation of the ligand binding domain of farnesoid X receptor. Insights into helix-12 stability and coactivator peptide stabilization in response to agonist binding.
PMID 15857131·J Med Chem·2005
8-other
Stereoselective synthesis and preliminary evaluation of (+)- and (-)-3-methyl-5-carboxy-thien-2-yl-glycine (3-MATIDA): identification of (+)-3-MATIDA as a novel mGluR1 competitive antagonist.
PMID 14871500·Farmaco·2004
7-preclinical
Binding mode of 6ECDCA, a potent bile acid agonist of the farnesoid X receptor (FXR).
PMID 12749886·Bioorg Med Chem Lett·2003
8-other
Molecular dynamics simulation of the ligand binding domain of mGluR1 in response to agonist and antagonist binding.
PMID 12825789·J Comput Aided Mol Des·2002
8-other
Metabotropic glutamate receptors: targets for therapy of cerebral ischaemia.
PMID 12540277·Expert Opin Ther Targets·2001
8-other
Synthesis and biological evaluation of 2-(3'-(1H-tetrazol-5-yl) bicyclo[1.1.1]pent-1-yl)glycine (S-TBPG), a novel mGlu1 receptor antagonist.
PMID 11249114·Bioorg Med Chem·2001
8-other
[Long-term therapy of benign prostatic hyperplasia. Our experience].
PMID 11346714·Minerva Urol Nefrol·2001
3-trial
Homology model of the closed, functionally active, form of the amino terminal domain of mGlur1.
PMID 11354667·Bioorg Med Chem·2001
8-other
QSAR and molecular modeling studies of baclofen analogues as GABA(B) agonists. Insights into the role of the aromatic moiety in GABA(B) binding and activation.
PMID 11356116·J Med Chem·2001
8-other
Modeling of poly(ADP-ribose)polymerase (PARP) inhibitors. Docking of ligands and quantitative structure-activity relationship analysis.
PMID 11689065·J Med Chem·2001
8-other
Evaluation of hydrophobic/hydrophilic balance of bile acids by comparative molecular field analysis (CoMFA).
PMID 10978726·Steroids·2000
8-other
Neural autonomic control in orthostatic intolerance.
PMID 19379844·Respir Physiol Neurobiol·2009
6-review
Molecular dynamics simulation of the heterodimeric mGluR2/5HT(2A) complex. An atomistic resolution study of a potential new target in psychiatric conditions.
PMID 19422244·J Chem Inf Model·2009
8-other
Inheritance of characters involved in fruit quality in a citrus interspecific allotetraploid somatic hybrid.
PMID 19425535·J Agric Food Chem·2009
8-other
Bulky 1,4-benzoxazine derivatives with antifungal activity.
PMID 19433362·Bioorg Med Chem·2009
7-preclinical
Synthesis and biological evaluation of 4,5-diphenyloxazolone derivatives on route towards selective COX-2 inhibitors.
PMID 19084295·Eur J Med Chem·2009
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1205 LANGHORNE NEWTOWN RD, SUITE 307
LANGHORNE, PA 19047 - Phone
- (215) 891-1430
Quick Facts
- NPI
- 1669496642
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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