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DR. ALEXANDER ENGELMAN M.D.
M.D.
Radiation Oncology Physician
NPI: 1679863658IndividualAccepts Medicare
Specialties, Licenses & Credentials
Radiation Oncology PhysicianPrimary
Radiology — Radiation Oncology
Code: 2085R0001X
ME128283(FL)
Education
GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE
Class of 2011
Research & Publications (20)
A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75.
PMID 19132083·PLoS Pathog·2009
8-other
Structural basis for functional tetramerization of lentiviral integrase.
PMID 19609359·PLoS Pathog·2009
8-other
In vivo biotinylation and capture of HIV-1 matrix and integrase proteins.
PMID 19490971·J Virol Methods·2009
8-other
The SET complex acts as a barrier to autointegration of HIV-1.
PMID 19266025·PLoS Pathog·2009
7-preclinical
Mechanistic and pharmacological analyses of HIV-1 integration.
PMID 19389610·Methods·2009
7-preclinical
Dynamic modulation of HIV-1 integrase structure and function by cellular lens epithelium-derived growth factor (LEDGF) protein.
PMID 18801737·J Biol Chem·2008
8-other
Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding.
PMID 18093980·J Biol Chem·2008
8-other
The lentiviral integrase binding protein LEDGF/p75 and HIV-1 replication.
PMID 18369482·PLoS Pathog·2008
6-review
Chromatinized templates reveal the requirement for the LEDGF/p75 PWWP domain during HIV-1 integration in vitro.
PMID 18174227·Nucleic Acids Res·2008
8-other
Identification of host proteins required for HIV infection through a functional genomic screen.
PMID 18187620·Science·2008
8-other
Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity.
PMID 18799576·J Virol·2008
7-preclinical
Structure-based mutagenesis of the integrase-LEDGF/p75 interface uncouples a strict correlation between in vitro protein binding and HIV-1 fitness.
PMID 16959283·Virology·2007
8-other
LEDGF/p75 interferes with the formation of synaptic nucleoprotein complexes that catalyze full-site HIV-1 DNA integration in vitro: implications for the mechanism of viral cDNA integration.
PMID 17258258·Virology·2007
8-other
Molecular mechanisms of HIV integration and therapeutic intervention.
PMID 17320002·Expert Rev Mol Med·2007
6-review
LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration.
PMID 17639082·Genes Dev·2007
7-preclinical
Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration.
PMID 17428871·J Virol·2007
8-other
Characterization of a replication-competent, integrase-defective human immunodeficiency virus (HIV)/simian virus 40 chimera as a powerful tool for the discovery and validation of HIV integrase inhibitors.
PMID 17287285·J Virol·2007
4-observational
Wild-type levels of human immunodeficiency virus type 1 infectivity in the absence of cellular emerin protein.
PMID 17035312·J Virol·2007
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 601 S ARMENIA AVE
TAMPA, FL 33609 - Phone
- (813) 353-8803
Quick Facts
- NPI
- 1679863658
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 15
- Publications
- 20
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