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THOMAS BRUICE, M.D., PH.D.
M.D., PH.D.
Clinical Pathology/Laboratory Medicine Physician
NPI: 1700326576Individual
Specialties, Licenses & Credentials
Clinical Pathology/Laboratory Medicine PhysicianPrimary
Pathology — Clinical Pathology/Laboratory Medicine
Code: 207ZP0105X
G60958(CA)
Research & Publications (20)
Computational approaches: reaction trajectories, structures, and atomic motions. Enzyme reactions and proficiency.
PMID 16895321·Chem Rev·2006
6-review
A view at the millennium: the efficiency of enzymatic catalysis.
PMID 11900517·Acc Chem Res·2002
6-review
Binding properties of positively charged deoxynucleic guanidine (DNG), AgTgAgTgAgT and DNG/DNA chimeras to DNA.
PMID 18514514·Bioorg Med Chem Lett·2008
8-other
Incorporation of positively charged ribonucleic guanidine linkages into oligodeoxyribonucleotides: Development of potent antisense agents.
PMID 18353646·Bioorg Med Chem Lett·2008
8-other
Mechanism of product specificity of AdoMet methylation catalyzed by lysine methyltransferases: transcriptional factor p53 methylation by histone lysine methyltransferase SET7/9.
PMID 18260647·Biochemistry·2008
8-other
Enzymatic mechanism and product specificity of SET-domain protein lysine methyltransferases.
PMID 18391193·Proc Natl Acad Sci U S A·2008
8-other
Complexation of single strand telomere and telomerase RNA template polyanions by deoxyribonucleic guanidine (DNG) polycations: plausible anticancer agents.
PMID 18063368·Bioorg Med Chem Lett·2008
8-other
Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8.
PMID 18512960·Biochemistry·2008
8-other
Temperature-dependent structure of the E x S complex of Bacillus stearothermophilus alcohol dehydrogenase.
PMID 17223705·Biochemistry·2007
8-other
Histone lysine methyltransferase SET7/9: formation of a water channel precedes each methyl transfer.
PMID 18044969·Biochemistry·2007
8-other
Catalytic mechanism and product specificity of rubisco large subunit methyltransferase: QM/MM and MD investigations.
PMID 17429949·Biochemistry·2007
8-other
Mechanism of methanol oxidation by quinoprotein methanol dehydrogenase.
PMID 17215371·Proc Natl Acad Sci U S A·2007
8-other
Low-frequency normal modes in horse liver alcohol dehydrogenase and motions of residues involved in the enzymatic reaction.
PMID 16737770·Biophys Chem·2007
7-preclinical
A quantum mechanics/molecular mechanics study of the catalytic mechanism and product specificity of viral histone lysine methyltransferase.
PMID 17676763·Biochemistry·2007
8-other
An investigation of the ionic and solvation patterns of dsDNG versus dsDNA by use of molecular dynamics simulations.
PMID 16527389·Biophys Chem·2007
8-other
Solid-phase synthesis of positively charged deoxynucleic guanidine (DNG) oligonucleotide incorporating 7-deazaguanine bases.
PMID 16945544·Bioorg Med Chem·2006
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 6783 PALERMI PL
CARLSBAD, CA 92011 - Phone
- (760) 438-4018
Quick Facts
- NPI
- 1700326576
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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