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SRINIVAS MANDALA, D.M.D
D.M.D
General Practice Dentistry
NPI: 1710208004Individual
Specialties, Licenses & Credentials
General Practice DentistryPrimary
Dentist — General Practice
Code: 1223G0001X
10572(NC)
Research & Publications (20)
Gastrointestinal stromal tumour of the rectum: report of a case and review of literature.
PMID 18300363·World J Gastroenterol·2008
5-case
Identification of Leu276 of the S1P1 receptor and Phe263 of the S1P3 receptor in interaction with receptor specific agonists by molecular modeling, site-directed mutagenesis, and affinity studies.
PMID 17170199·Mol Pharmacol·2007
7-preclinical
SAR studies of 3-arylpropionic acids as potent and selective agonists of sphingosine-1-phosphate receptor-1 (S1P1) with enhanced pharmacokinetic properties.
PMID 17092714·Bioorg Med Chem Lett·2007
7-preclinical
Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina.
PMID 17710232·J Clin Invest·2007
7-preclinical
2-Aryl(pyrrolidin-4-yl)acetic acids are potent agonists of sphingosine-1-phosphate (S1P) receptors.
PMID 16621543·Bioorg Med Chem Lett·2006
7-preclinical
Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes.
PMID 16697189·Bioorg Med Chem Lett·2006
7-preclinical
Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor.
PMID 16682185·Bioorg Med Chem Lett·2006
7-preclinical
2,5-Disubstituted pyrrolidine carboxylates as potent, orally active sphingosine-1-phosphate (S1P) receptor agonists.
PMID 16580205·Bioorg Med Chem Lett·2006
7-preclinical
Sphingosine-1-phosphate agonists increase macrophage homing, lymphocyte contacts, and endothelial junctional complex formation in murine lymph nodes.
PMID 16301618·J Immunol·2005
7-preclinical
Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3.
PMID 16190743·J Med Chem·2005
7-preclinical
Sphingosine 1-phosphate receptor agonist FTY720-phosphate causes marginal zone B cell displacement.
PMID 15894589·J Leukoc Biol·2005
7-preclinical
The S1P-analog FTY720 differentially modulates T-cell homing via HEV: T-cell-expressed S1P1 amplifies integrin activation in peripheral lymph nodes but not in Peyer patches.
PMID 15870184·Blood·2005
7-preclinical
Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720.
PMID 15336258·Bioorg Med Chem·2004
7-preclinical
A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists.
PMID 15615513·J Med Chem·2004
7-preclinical
Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.
PMID 15459201·J Biol Chem·2004
7-preclinical
Design and synthesis of conformationally constrained 3-(N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors.
PMID 15341940·Bioorg Med Chem Lett·2004
7-preclinical
Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice.
PMID 15265669·J Neuroimmunol·2004
4-observational
Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists.
PMID 15177461·Bioorg Med Chem Lett·2004
7-preclinical
The discovery of 3-(N-alkyl)aminopropylphosphonic acids as potent S1P receptor agonists.
PMID 15177460·Bioorg Med Chem Lett·2004
7-preclinical
Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720.
PMID 15149705·Bioorg Med Chem Lett·2004
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1481 RICHARDSON RD STE 111
APEX, NC 27523 - Phone
- (919) 446-3131
Quick Facts
- NPI
- 1710208004
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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