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EDWARD PROCHOWNIK, MD

MD

Pediatric Hematology & Oncology Physician

NPI: 1720053275Individual

Specialties, Licenses & Credentials

Specialist

Specialist

Code: 174400000X

MD046934L(PA)
Pediatric Hematology & Oncology PhysicianPrimary

Pediatrics — Pediatric Hematology-Oncology

Code: 2080P0207X

MD046934L(PA)

Research & Publications (20)

c-Myc: linking transformation and genomic instability.
PMID 18781952·Curr Mol Med·2008
6-review
The ever expanding role for c-Myc in promoting genomic instability.
PMID 17426456·Cell Cycle·2007
6-review
Functional and physical communication between oncoproteins and tumor suppressors.
PMID 16143828·Cell Mol Life Sci·2005
6-review
c-Myc as a therapeutic target in cancer.
PMID 15056059·Expert Rev Anticancer Ther·2004
6-review
Modularity of the oncoprotein-like properties of platelet glycoprotein Ibalpha.
PMID 19017648·J Biol Chem·2009
7-preclinical
Multiple independent binding sites for small-molecule inhibitors on the oncoprotein c-Myc.
PMID 19432426·J Am Chem Soc·2009
8-other
Discovery of novel Myc-Max heterodimer disruptors with a three-dimensional pharmacophore model.
PMID 19215087·J Med Chem·2009
7-preclinical
Regulation of reactive oxygen species homeostasis by peroxiredoxins and c-Myc.
PMID 19098005·J Biol Chem·2009
7-preclinical
Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice.
PMID 18509642·Cancer Chemother Pharmacol·2009
7-preclinical
Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small molecules.
PMID 19022175·Chem Biol·2008
8-other
c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle.
PMID 17906696·Oncogene·2008
8-other
Transformation, genomic instability and senescence mediated by platelet/megakaryocyte glycoprotein Ibalpha.
PMID 17873907·Oncogene·2008
7-preclinical
C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells.
PMID 18679422·Oncogene·2008
8-other
c-Myc-mediated genomic instability proceeds via a megakaryocytic endomitosis pathway involving Gp1balpha.
PMID 17360671·Proc Natl Acad Sci U S A·2007
4-observational
Dual role for SUMO E2 conjugase Ubc9 in modulating the transforming and growth-promoting properties of the HMGA1b architectural transcription factor.
PMID 17350957·J Biol Chem·2007
7-preclinical
The high-mobility group A1 gene up-regulates cyclooxygenase 2 expression in uterine tumorigenesis.
PMID 17483309·Cancer Res·2007
7-preclinical
Improved low molecular weight Myc-Max inhibitors.
PMID 17876039·Mol Cancer Ther·2007
8-other
The negative c-Myc target onzin affects proliferation and apoptosis via its obligate interaction with phospholipid scramblase 1.
PMID 16611984·Mol Cell Biol·2006
7-preclinical
A functional hierarchy for c-Myc target genes? Lessons from MT-MC1.
PMID 16481743·Cell Cycle·2006
7-preclinical
Deregulation of common genes by c-Myc and its direct target, MT-MC1.
PMID 16365299·Proc Natl Acad Sci U S A·2005
7-preclinical

Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.

Contact & Hours

Address
3705 5TH AVE, ROOM 4B385
PITTSBURGH, PA 15213

Location

Practice Location

3705 5TH AVE, PITTSBURGH, PA
(412) 692-5055

Quick Facts

NPI
1720053275
Entity Type
Individual
Gender
Male
Medicare
Not confirmed
Specialties
2
Locations
1
Publications
20

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