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GEORGE CHACONAS, MD
MD
Family Medicine Physician
NPI: 1720069354IndividualAccepts Medicare
Specialties, Licenses & Credentials
Family Medicine PhysicianPrimary
Family Medicine
Code: 207Q00000X
0101-038267(VA)
CMS Specialties
PrimaryFAMILY PRACTICE
Education
EASTERN VIRGINIA MEDICAL SCHOOL
Class of 1984
Research & Publications (20)
High-throughput screening identifies three inhibitor classes of the telomere resolvase from the lyme disease spirochete.
PMID 19596868·Antimicrob Agents Chemother·2009
7-preclinical
Identification of the determinant conferring permissive substrate usage in the telomere resolvase, ResT.
PMID 19561077·J Biol Chem·2009
8-other
Characterization and in vitro reaction properties of 19 unique hairpin telomeres from the linear plasmids of the lyme disease spirochete.
PMID 19122193·J Biol Chem·2009
8-other
Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host.
PMID 18833295·PLoS Pathog·2008
7-preclinical
Real-time high resolution 3D imaging of the lyme disease spirochete adhering to and escaping from the vasculature of a living host.
PMID 18566656·PLoS Pathog·2008
7-preclinical
Purification and properties of the plasmid maintenance proteins from the Borrelia burgdorferi linear plasmid lp17.
PMID 18375548·J Bacteriol·2008
8-other
The role of VlsE antigenic variation in the Lyme disease spirochete: persistence through a mechanism that differs from other pathogens.
PMID 17714442·Mol Microbiol·2007
7-preclinical
Telomere resolution by Borrelia burgdorferi ResT through the collaborative efforts of tethered DNA binding domains.
PMID 17462009·Mol Microbiol·2007
8-other
Topology-dependent transcription in linear and circular plasmids of the segmented genome of Borrelia burgdorferi.
PMID 17241200·Mol Microbiol·2007
8-other
Unexpected twist: harnessing the energy in positive supercoils to control telomere resolution.
PMID 16999829·Mol Microbiol·2006
8-other
Differential telomere processing by Borrelia telomere resolvases in vitro but not in vivo.
PMID 16936037·J Bacteriol·2006
8-other
Hairpin telomeres and genome plasticity in Borrelia: all mixed up in the end.
PMID 16238614·Mol Microbiol·2005
6-review
Mapping of essential replication functions of the linear plasmid lp17 of B. burgdorferi by targeted deletion walking.
PMID 15948955·Mol Microbiol·2005
8-other
Fusion of hairpin telomeres by the B. burgdorferi telomere resolvase ResT implications for shaping a genome in flux.
PMID 15780935·Mol Cell·2005
8-other
3D reconstruction of the Mu transposase and the Type 1 transpososome: a structural framework for Mu DNA transposition.
PMID 15774720·Genes Dev·2005
8-other
Catalytic residues of the telomere resolvase ResT: a pattern similar to, but distinct from, tyrosine recombinases and type IB topoisomerases.
PMID 15471873·J Biol Chem·2004
8-other
Mixing active-site components: a recipe for the unique enzymatic activity of a telomere resolvase.
PMID 15365172·Proc Natl Acad Sci U S A·2004
8-other
Effect of mutations in the C-terminal domain of Mu B on DNA binding and interactions with Mu A transposase.
PMID 12791691·J Biol Chem·2003
8-other
Sequence-specific recognition but position-dependent cleavage of two distinct telomeres by the Borrelia burgdorferi telomere resolvase, ResT.
PMID 12753185·Mol Microbiol·2003
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 6675 BOOKER T. WASHINGTON HWY
WIRTZ, VA 24184 - Phone
- (540) 721-2118
Quick Facts
- NPI
- 1720069354
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 42
- Publications
- 20
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