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JOHN MANIS, M.D.
Hematology & Oncology Physician
NPI: 1720072424IndividualAccepts Medicare
Specialties, Licenses & Credentials
Hematology & Oncology PhysicianPrimary
Internal Medicine — Hematology & Oncology
Code: 207RH0003X
72999(MA)
Education
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
Class of 1998
Research & Publications (20)
Knock out, knock in, knock down--genetically manipulated mice and the Nobel Prize.
PMID 18077807·N Engl J Med·2007
7-preclinical
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.
PMID 15077110·Nat Immunol·2004
7-preclinical
Elucidation of a downstream boundary of the 3' IgH regulatory region.
PMID 12531286·Mol Immunol·2003
7-preclinical
IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells.
PMID 11970883·Immunity·2002
7-preclinical
Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice.
PMID 19196992·Proc Natl Acad Sci U S A·2009
7-preclinical
Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching.
PMID 19064702·J Exp Med·2008
7-preclinical
B-cell receptor cross-linking delays activation-induced cytidine deaminase induction and inhibits class-switch recombination to IgE.
PMID 17900678·J Allergy Clin Immunol·2008
7-preclinical
Integrative analysis reveals 53BP1 copy loss and decreased expression in a subset of human diffuse large B-cell lymphomas.
PMID 17637749·Oncogene·2008
8-other
IgH class switching and translocations use a robust non-classical end-joining pathway.
PMID 17713479·Nature·2007
7-preclinical
SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis.
PMID 18031698·Immunity·2007
7-preclinical
Evolution of the immunoglobulin heavy chain class switch recombination mechanism.
PMID 17560275·Adv Immunol·2007
6-review
S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase.
PMID 17980632·Immunity·2007
7-preclinical
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals.
PMID 16427009·Mol Cell·2006
7-preclinical
H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.
PMID 16427010·Mol Cell·2006
7-preclinical
53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis.
PMID 16492765·Proc Natl Acad Sci U S A·2006
7-preclinical
Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations.
PMID 16934538·DNA Repair (Amst)·2006
6-review
The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation.
PMID 16251902·Nature·2005
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 16 RUTLAND SQ
BOSTON, MA 02118 - Phone
- (617) 919-2618
Quick Facts
- NPI
- 1720072424
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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