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CATHY MIELE, MD
MD
Obstetrics & Gynecology Physician
NPI: 1730149378Individual
Specialties, Licenses & Credentials
Obstetrics & Gynecology PhysicianPrimary
Obstetrics & Gynecology
Code: 207V00000X
011910(ME)
Research & Publications (20)
Glucose regulates diacylglycerol intracellular levels and protein kinase C activity by modulating diacylglycerol kinase subcellular localization.
PMID 17675299·J Biol Chem·2007
7-preclinical
PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells.
PMID 17327429·Diabetes·2007
7-preclinical
Human glycated albumin affects glucose metabolism in L6 skeletal muscle cells by impairing insulin-induced insulin receptor substrate (IRS) signaling through a protein kinase C alpha-mediated mechanism.
PMID 12970360·J Biol Chem·2003
7-preclinical
Tyrosine phosphorylation of insulin receptor substrates during ischemia/reperfusion-induced apoptosis in rat liver.
PMID 18679708·Langenbecks Arch Surg·2009
7-preclinical
Efficacy and tolerability of olmesartan medoxomil combined with amlodipine in patients with moderate to severe hypertension after amlodipine monotherapy: a randomized, double-blind, parallel-group, multicentre study.
PMID 19067471·Clin Drug Investig·2009
4-observational
Efficacy and safety of a stepped-care regimen using olmesartan medoxomil, amlodipine and hydrochlorothiazide in patients with moderate-to-severe hypertension: an open-label, long-term study.
PMID 19432498·Clin Drug Investig·2009
3-trial
The cannabinoid CB1 receptor antagonist rimonabant stimulates 2-deoxyglucose uptake in skeletal muscle cells by regulating the expression of phosphatidylinositol-3-kinase.
PMID 18801918·Mol Pharmacol·2008
7-preclinical
In skeletal muscle advanced glycation end products (AGEs) inhibit insulin action and induce the formation of multimolecular complexes including the receptor for AGEs.
PMID 18955497·J Biol Chem·2008
7-preclinical
Molecular cloning and characterization of the human PED/PEA-15 gene promoter reveal antagonistic regulation by hepatocyte nuclear factor 4alpha and chicken ovalbumin upstream promoter transcription factor II.
PMID 18765665·J Biol Chem·2008
7-preclinical
Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism.
PMID 18644868·Mol Cell Biol·2008
7-preclinical
Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells.
PMID 18541525·J Biol Chem·2008
7-preclinical
Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15.
PMID 18420420·Protein Expr Purif·2008
8-other
Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells.
PMID 17242212·Mol Cell Biol·2007
7-preclinical
Phorbol esters induce intracellular accumulation of the anti-apoptotic protein PED/PEA-15 by preventing ubiquitinylation and proteasomal degradation.
PMID 17227770·J Biol Chem·2007
8-other
Involvement of protein kinase B and mitogen-activated protein kinases in experimental normothermic liver ischaemia-reperfusion injury.
PMID 16671069·Br J Surg·2006
7-preclinical
Alterations in protein tyrosine kinase pathways in rat liver following normothermic ischemia-reperfusion.
PMID 17175272·Transplant Proc·2006
7-preclinical
The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes.
PMID 17021921·Diabetologia·2006
8-other
Thrombin-activated platelets induce proliferation of human skin fibroblasts by stimulating autocrine production of insulin-like growth factor-1.
PMID 17015410·FASEB J·2006
8-other
Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling.
PMID 16314505·Mol Cell Biol·2005
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 462 MAIN ST, SUITE 1
SPRINGVALE, ME 04083 - Phone
- (207) 206-7270
Quick Facts
- NPI
- 1730149378
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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