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RONALD GRAEFF, MD
MD
Allergy & Immunology Physician
NPI: 1730172339Individual
Specialties, Licenses & Credentials
Allergy & Immunology PhysicianPrimary
Allergy & Immunology
Code: 207K00000X
30479(IA)
Pediatric Pulmonology Physician
Pediatrics — Pediatric Pulmonology
Code: 2080P0214X
30479(IA)
Research & Publications (20)
Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase.
PMID 19640846·J Biol Chem·2009
7-preclinical
Mechanism of cyclizing NAD to cyclic ADP-ribose by ADP-ribosyl cyclase and CD38.
PMID 19640843·J Biol Chem·2009
7-preclinical
Correcting autoimmune anomalies in autoimmune disorders by immunological means, employing the modified vaccination technique.
PMID 19393215·Autoimmun Rev·2009
6-review
Preventing and treating chronic disorders using the modified vaccination technique.
PMID 19273320·Front Biosci (Landmark Ed)·2009
6-review
Conformational Closure of the Catalytic Site of Human CD38 Induced by Calcium.
PMID 19117080·Biochemistry·2008
8-other
Conformational Closure of the Catalytic Site of Human CD38 Induced by Calcium (dagger) (double dagger).
PMID 19115832·Biochemistry·2008
8-other
Hierarchical and helical self-assembly of ADP-ribosyl cyclase into large-scale protein microtubes.
PMID 18956900·J Phys Chem B·2008
8-other
Ca(2+) signaling occurs via second messenger release from intraorganelle synthesis sites.
PMID 18951023·Curr Biol·2008
7-preclinical
Covalent and noncovalent intermediates of an NAD utilizing enzyme, human CD38.
PMID 18940667·Chem Biol·2008
8-other
Catalysis-associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog.
PMID 17591784·J Biol Chem·2007
8-other
Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38.
PMID 17182614·J Biol Chem·2007
8-other
Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis.
PMID 16951430·J Biol Chem·2006
4-observational
Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine nicotinic acid adenine dinucleotide phosphate (NAADP) synthesis and hydrolysis activities.
PMID 16861223·J Biol Chem·2006
8-other
ADP-ribosyl cyclase; crystal structures reveal a covalent intermediate.
PMID 15016363·Structure·2004
7-preclinical
Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells.
PMID 12852785·Biochem J·2003
8-other
High throughput fluorescence-based assays for cyclic ADP-ribose, NAADP, and their metabolic enzymes.
PMID 12769681·Comb Chem High Throughput Screen·2003
8-other
Evidence for a causal role of CD38 expression in granulocytic differentiation of human HL-60 cells.
PMID 12386160·J Biol Chem·2002
8-other
A novel cycling assay for nicotinic acid-adenine dinucleotide phosphate with nanomolar sensitivity.
PMID 12117413·Biochem J·2002
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 410 N 12TH ST STE 100, MAHASKA HEALTH PARTNERSHIP
OSKALOOSA, IA 52577 - Phone
- (641) 672-3360
Quick Facts
- NPI
- 1730172339
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 1
- Publications
- 20
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