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NICHOLAS BUMPUS, PHARMD
PHARMD
Pharmacist
NPI: 1750053781Individual
Specialties, Licenses & Credentials
PharmacistPrimary
Pharmacist
Code: 183500000X
03233967(OH)
Research & Publications (5)
Investigation of the mechanisms underlying the differential effects of the K262R mutation of P450 2B6 on catalytic activity.
PMID 18621926·Mol Pharmacol·2008
8-other
Mechanism-based inactivation of human cytochromes p450s: experimental characterization, reactive intermediates, and clinical implications.
PMID 18052110·Chem Res Toxicol·2008
6-review
Metabolism of efavirenz and 8-hydroxyefavirenz by P450 2B6 leads to inactivation by two distinct mechanisms.
PMID 16611850·J Pharmacol Exp Ther·2006
4-observational
The naturally occurring cytochrome P450 (P450) 2B6 K262R mutant of P450 2B6 exhibits alterations in substrate metabolism and inactivation.
PMID 15769884·Drug Metab Dispos·2005
4-observational
Metabolism of N,N',N"-triethylenethiophosphoramide by CYP2B1 and CYP2B6 results in the inactivation of both isoforms by two distinct mechanisms.
PMID 15121764·J Pharmacol Exp Ther·2004
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 2900 STELZER RD
COLUMBUS, OH 43219 - Phone
- (614) 337-0397
Quick Facts
- NPI
- 1750053781
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 5
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