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GEORGE SIEGFRIED, M.D.
M.D.
Plastic Surgery Physician
NPI: 1750353108Individual
Specialties, Licenses & Credentials
Plastic Surgery PhysicianPrimary
Plastic Surgery
Code: 208200000X
AA1858(AK)
Research & Publications (13)
Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7.
PMID 18664504·Gut·2008
7-preclinical
Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis.
PMID 18617693·Circ Res·2008
7-preclinical
Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells.
PMID 18064302·J Clin Invest·2008
7-preclinical
Opposing function of the proprotein convertases furin and PACE4 on breast cancer cells' malignant phenotypes: role of tissue inhibitors of metalloproteinase-1.
PMID 17909005·Cancer Res·2007
8-other
Endo/exo-proteolysis in neoplastic progression and metastasis.
PMID 16133424·J Mol Med (Berl)·2005
6-review
Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases.
PMID 16007151·Oncogene·2005
7-preclinical
The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis.
PMID 12782675·J Clin Invest·2003
7-preclinical
The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity.
PMID 12670890·Cancer Res·2003
7-preclinical
Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy.
PMID 12057895·Am J Pathol·2002
6-review
Mechanism of inhibition of endothelin-1-stimulated proteoglycan and collagen synthesis in rat articular chondrocytes.
PMID 12027406·Cytokine·2002
7-preclinical
Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions.
PMID 11402025·J Biol Chem·2001
7-preclinical
Developmental expression and tissue distribution of Phex protein: effect of the Hyp mutation and relationship to bone markers.
PMID 10934642·J Bone Miner Res·2000
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1200 AIRPORT HEIGHTS DR, #190
ANCHORAGE, AK 99508 - Phone
- (907) 276-2216
Quick Facts
- NPI
- 1750353108
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 13
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