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KAREN ROSSMAN, PH.D.
PH.D.
Psychologist
NPI: 1750447348Individual
Specialties, Licenses & Credentials
PsychologistPrimary
Psychologist
Code: 103T00000X
PY00001970(WA)
Research & Publications (20)
Role of the C-terminal SH3 domain and N-terminal tyrosine phosphorylation in regulation of Tim and related Dbl-family proteins.
PMID 18537266·Biochemistry·2008
7-preclinical
Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.
PMID 17704816·Nat Struct Mol Biol·2007
8-other
Auto-inhibition of the Dbl family protein Tim by an N-terminal helical motif.
PMID 17337446·J Biol Chem·2007
7-preclinical
The Dbs PH domain contributes independently to membrane targeting and regulation of guanine nucleotide-exchange activity.
PMID 17007612·Biochem J·2006
7-preclinical
GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors.
PMID 15688002·Nat Rev Mol Cell Biol·2005
6-review
A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs.
PMID 15723800·Curr Biol·2005
4-observational
Larger than Dbl: new structural insights into RhoA activation.
PMID 15817389·Trends Biochem Sci·2005
6-review
PH domain of ELMO functions in trans to regulate Rac activation via Dock180.
PMID 15247908·Nat Struct Mol Biol·2004
7-preclinical
Requirement for C-terminal sequences in regulation of Ect2 guanine nucleotide exchange specificity and transformation.
PMID 15073184·J Biol Chem·2004
7-preclinical
Crystal structure of the DH/PH fragment of Dbs without bound GTPase.
PMID 15274927·Structure·2004
7-preclinical
Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.
PMID 14506234·J Biol Chem·2003
7-preclinical
Established and emerging fluorescence-based assays for G-protein function: Ras-superfamily GTPases.
PMID 12769685·Comb Chem High Throughput Screen·2003
4-observational
Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting.
PMID 12525493·J Biol Chem·2003
7-preclinical
Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation.
PMID 12637522·J Biol Chem·2003
7-preclinical
Functional analysis of cdc42 residues required for Guanine nucleotide exchange.
PMID 12401782·J Biol Chem·2002
8-other
A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
PMID 11889037·EMBO J·2002
7-preclinical
RhoGEF specificity mutants implicate RhoA as a target for Dbs transforming activity.
PMID 12215546·Mol Cell Biol·2002
7-preclinical
Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
PMID 12006984·Nat Struct Biol·2002
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 127 E INTERCITY AVE, SUITE A
EVERETT, WA 98208 - Phone
- (425) 347-7275
Quick Facts
- NPI
- 1750447348
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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