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JUSTIN YINGLING, PHARMD, RPH
PHARMD, RPH
Pharmacist
NPI: 1760084545Individual
Specialties, Licenses & Credentials
PharmacistPrimary
Pharmacist
Code: 183500000X
0202214556(VA)
Research & Publications (20)
Developing and applying a gene functional association network for anti-angiogenic kinase inhibitor activity assessment in an angiogenesis co-culture model.
PMID 18518970·BMC Genomics·2008
8-other
Cancer-associated transforming growth factor beta type II receptor gene mutant causes activation of bone morphogenic protein-Smads and invasive phenotype.
PMID 18339844·Cancer Res·2008
8-other
Optimization of a dihydropyrrolopyrazole series of transforming growth factor-beta type I receptor kinase domain inhibitors: discovery of an orally bioavailable transforming growth factor-beta receptor type I inhibitor as antitumor agent.
PMID 18314943·J Med Chem·2008
7-preclinical
TGF-beta signalling-related markers in cancer patients with bone metastasis.
PMID 18270872·Biomarkers·2008
8-other
Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division.
PMID 18267077·Cell·2008
7-preclinical
Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-beta kinase antagonist, in mice.
PMID 18039567·Eur J Cancer·2008
7-preclinical
Analysis of pathway activity in primary tumors and NCI60 cell lines using gene expression profiling data.
PMID 17572360·Genomics Proteomics Bioinformatics·2007
8-other
Assay optimization: a statistical design of experiments approach.
PMID 17416307·Clin Lab Med·2007
8-other
Three mechanistically distinct kinase assays compared: Measurement of intrinsic ATPase activity identified the most comprehensive set of ITK inhibitors.
PMID 17166826·J Biomol Screen·2007
4-observational
Characterization and development of a peptide substrate-based phosphate transfer assay for the human vascular endothelial growth factor receptor-2 tyrosine kinase.
PMID 17141171·Anal Biochem·2007
8-other
Smad4-dependent regulation of urokinase plasminogen activator secretion and RNA stability associated with invasiveness by autocrine and paracrine transforming growth factor-beta.
PMID 16959768·J Biol Chem·2006
8-other
Dihydropyrrolopyrazole transforming growth factor-beta type I receptor kinase domain inhibitors: a novel benzimidazole series with selectivity versus transforming growth factor-beta type II receptor kinase and mixed lineage kinase-7.
PMID 16539403·J Med Chem·2006
7-preclinical
Activated type I TGFbeta receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression.
PMID 16186809·Oncogene·2006
7-preclinical
Role of 14-3-3 proteins in eukaryotic signaling and development.
PMID 16125003·Curr Top Dev Biol·2005
6-review
Kinetic characterization of novel pyrazole TGF-beta receptor I kinase inhibitors and their blockade of the epithelial-mesenchymal transition.
PMID 15709742·Biochemistry·2005
7-preclinical
Development of TGF-beta signalling inhibitors for cancer therapy.
PMID 15573100·Nat Rev Drug Discov·2004
6-review
Transforming the TGFbeta pathway: convergence of distinct lead generation strategies on a novel kinase pharmacophore for TbetaRI (ALK5).
PMID 15338953·Curr Opin Drug Discov Devel·2004
6-review
Novel and potent transforming growth factor beta type I receptor kinase domain inhibitor: 7-amino 4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinolines.
PMID 15177480·Bioorg Med Chem Lett·2004
8-other
Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain.
PMID 15177479·Bioorg Med Chem Lett·2004
7-preclinical
Synthesis and activity of new aryl- and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain.
PMID 12954047·J Med Chem·2003
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 506 E NELSON ST
LEXINGTON, VA 24450 - Phone
- (814) 327-0124
Quick Facts
- NPI
- 1760084545
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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