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LUCE CANTIN, M.D., FRCPC
M.D., FRCPC
Diagnostic Radiology Physician
NPI: 1760624589Individual
Specialties, Licenses & Credentials
Diagnostic Radiology PhysicianPrimary
Radiology — Diagnostic Radiology
Code: 2085R0202X
235745(MA)
Research & Publications (20)
Indanylacetic acid derivatives carrying aryl-pyridyl and aryl-pyrimidinyl tail groups--new classes of PPAR gamma/delta and PPAR alpha/gamma/delta agonists.
PMID 17157013·Bioorg Med Chem Lett·2007
4-observational
Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition.
PMID 19075558·Biochemistry·2008
8-other
Running, swimming and diving modifies neuroprotecting globins in the mammalian brain.
PMID 18089537·Proc Biol Sci·2008
7-preclinical
The crystal structure of human Delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism.
PMID 18624455·Biochemistry·2008
8-other
Indanylacetic acids as PPAR-delta activator insulin sensitizers.
PMID 17601734·Bioorg Med Chem Lett·2007
8-other
Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.
PMID 17442338·J Mol Biol·2007
7-preclinical
Structural characterization of the human androgen receptor ligand-binding domain complexed with EM5744, a rationally designed steroidal ligand bearing a bulky chain directed toward helix 12.
PMID 17711855·J Biol Chem·2007
8-other
Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.
PMID 17034817·J Mol Biol·2006
7-preclinical
Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity.
PMID 16641486·Protein Sci·2006
4-observational
Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains.
PMID 16298527·Bioorg Med Chem Lett·2006
7-preclinical
[The "objective" evaluation of the treatments in the mental health or when the clinical research is reduced to an experimental method].
PMID 16170435·Sante Ment Que·2005
8-other
Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen.
PMID 15929998·Protein Sci·2005
4-observational
Loop relaxation, a mechanism that explains the reduced specificity of rabbit 20alpha-hydroxysteroid dehydrogenase, a member of the aldo-keto reductase superfamily.
PMID 15123423·J Mol Biol·2004
4-observational
Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids.
PMID 12899831·J Mol Biol·2003
8-other
Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors.
PMID 12723947·J Med Chem·2003
7-preclinical
Expression, crystallization and preliminary X-ray analysis of human and rabbit 20alpha-hydroxysteroid dehydrogenases in complex with NADP(H) and various steroid substrates.
PMID 11752791·Acta Crystallogr D Biol Crystallogr·2002
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 330 BROOKLINE AVE
BOSTON, MA 02215 - Phone
- (617) 667-3000
Quick Facts
- NPI
- 1760624589
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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