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DARELL BIGNER, M.D., PH.D.
M.D., PH.D.
Neurology Physician
NPI: 1760768337Individual
Specialties, Licenses & Credentials
Neurology PhysicianPrimary
Psychiatry & Neurology — Neurology
Code: 2084N0400X
15217(NC)
Research & Publications (20)
Tyrosine phosphorylation of the human glutathione S-transferase P1 by epidermal growth factor receptor.
PMID 19254954·J Biol Chem·2009
7-preclinical
Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma.
PMID 19204199·J Clin Oncol·2009
3-trial
Glioblastoma multiforme: a review of where we have been and where we are going.
PMID 19555299·Expert Opin Investig Drugs·2009
6-review
Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy.
PMID 19514083·Cancer·2009
8-other
A sphingosine kinase inhibitor induces cell death in temozolomide resistant glioblastoma cells.
PMID 19597728·Cancer Chemother Pharmacol·2009
8-other
Human exposure to selected animal neurocarcinogens: a biomarker-based assessment and implications for brain tumor epidemiology.
PMID 19466671·J Toxicol Environ Health B Crit Rev·2009
6-review
Glioblastoma multiforme: a review of therapeutic targets.
PMID 19409033·Expert Opin Ther Targets·2009
6-review
Association between glioma and history of allergies, asthma, and eczema: a case-control study with three groups of controls.
PMID 19336556·Cancer Epidemiol Biomarkers Prev·2009
4-observational
Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma.
PMID 19289491·Neuro Oncol·2009
3-trial
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma.
PMID 19270706·Nat Genet·2009
8-other
Bifunctional DNA alkylator 1,3-bis(2-chloroethyl)-1-nitrosourea activates the ATR-Chk1 pathway independently of the mismatch repair pathway.
PMID 19261750·Mol Pharmacol·2009
8-other
Heat shock protein 70-binding protein 1 is highly expressed in high-grade gliomas, interacts with multiple heat shock protein 70 family members, and specifically binds brain tumor cell surfaces.
PMID 19659607·Cancer Sci·2009
7-preclinical
Phase II trial of Gliadel plus O6-benzylguanine in adults with recurrent glioblastoma multiforme.
PMID 19188181·Clin Cancer Res·2009
3-trial
Aptamers selected against the unglycosylated EGFRvIII ectodomain and delivered intracellularly reduce membrane-bound EGFRvIII and induce apoptosis.
PMID 19040357·Biol Chem·2009
7-preclinical
BCNU-sequestration by metallothioneins may contribute to resistance in a medulloblastoma cell line.
PMID 18633619·Cancer Chemother Pharmacol·2009
8-other
Treatment of HER2-positive breast carcinomatous meningitis with intrathecal administration of alpha-particle-emitting (211)At-labeled trastuzumab.
PMID 19647172·Nucl Med Biol·2009
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- DUKE UNIVERSITY MEDICAL CTR, MSRB-1, ROOM 177, RESEARCH DRIVE, BOX 3156
DURHAM, NC 27710 - Phone
- (919) 684-5018
Quick Facts
- NPI
- 1760768337
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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