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EVAN KHARASCH, MD
MD
Anesthesiology Physician
NPI: 1780602219IndividualAccepts Medicare
Specialties, Licenses & Credentials
Anesthesiology PhysicianPrimary
Anesthesiology
Code: 207L00000X
2005030236(MO)
CMS Specialties
PrimaryANESTHESIOLOGY
Education
NORTHWESTERN UNIVERSITY FEINBERG MEDICAL SCHOOL
Class of 1984
Clinical Trials (4)
4
Linked Trials
0
Recruiting
3
With Results
Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)
NCT03726268COMPLETEDPHASE4PRINCIPAL_INVESTIGATOR
Clinical Study of Generic and Brand Bupropion in Depression
NCT02209597COMPLETEDPHASE4PRINCIPAL_INVESTIGATOR
Methadone in Pediatric Anesthesia
NCT00921843COMPLETEDPHASE4PRINCIPAL_INVESTIGATOR
Perioperative Inflammation and Cyclooxygenase 2 (COX-2)
NCT00122096COMPLETEDPHASE4PRINCIPAL_INVESTIGATOR
Research & Publications (20)
Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity.
PMID 19232844·Drug Alcohol Depend·2009
8-other
Stereoselective bupropion hydroxylation as an in vivo phenotypic probe for cytochrome P4502B6 (CYP2B6) activity.
PMID 18287571·J Clin Pharmacol·2008
8-other
Rapid clinical induction of hepatic cytochrome P4502B6 activity by ritonavir.
PMID 18285471·Antimicrob Agents Chemother·2008
3-trial
New insights into the mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 2): Identification of nephrotoxic metabolites.
PMID 17006073·Anesthesiology·2006
7-preclinical
New insights into the mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 1): Identification of the nephrotoxic metabolic pathway.
PMID 17006072·Anesthesiology·2006
7-preclinical
Methadone pharmacokinetics are independent of cytochrome P4503A (CYP3A) activity and gastrointestinal drug transport: insights from methadone interactions with ritonavir/indinavir.
PMID 19225389·Anesthesiology·2009
4-observational
The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine.
PMID 19515968·J Pharmacol Exp Ther·2009
4-observational
Sevoflurane formulation water content influences degradation by Lewis acids in vaporizers.
PMID 19448204·Anesth Analg·2009
8-other
Contemporary clinical opioid use: opportunities and challenges.
PMID 19567709·Mayo Clin Proc·2009
8-other
Journal-related and other special activities at the 2008 American Society of Anesthesiologists Annual Meeting.
PMID 18754137·Anesthesiology·2008
8-other
Contribution of itraconazole metabolites to inhibition of CYP3A4 in vivo.
PMID 17495874·Clin Pharmacol Ther·2008
3-trial
Stereoselective metabolism of bupropion by cytochrome P4502B6 (CYP2B6) and human liver microsomes.
PMID 18219560·Pharm Res·2008
8-other
Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: I. Evidence against CYP3A mediation of methadone clearance.
PMID 19238655·Clin Pharmacol Ther·2008
3-trial
Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities.
PMID 19238656·Clin Pharmacol Ther·2008
3-trial
Role of CYP2B6 in stereoselective human methadone metabolism.
PMID 18292673·Anesthesiology·2008
4-observational
Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolam.
PMID 17554244·Clin Pharmacol Ther·2007
3-trial
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1 BARNES JEWISH HOSPITAL PLZ
SAINT LOUIS, MO 63110 - Phone
- (314) 362-6973
Quick Facts
- NPI
- 1780602219
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 42
- Clinical Trials
- 4
- Publications
- 20
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