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GALE BEARDSLEY, M.D.
M.D.
Psychiatry Physician
NPI: 1790789600Individual
Specialties, Licenses & Credentials
Psychiatry PhysicianPrimary
Psychiatry & Neurology — Psychiatry
Code: 2084P0800X
MD4083(HI)G151697(CA)
Research & Publications (13)
Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase.
PMID 17324932·J Biol Chem·2007
7-preclinical
Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates.
PMID 14966129·J Biol Chem·2004
8-other
Catalytic mechanism of the cyclohydrolase activity of human aminoimidazole carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase.
PMID 14756554·Biochemistry·2004
4-observational
Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.
PMID 14654523·Clin Cancer Res·2003
6-review
Sequence alterations in the reduced folate carrier are observed in osteosarcoma tumor samples.
PMID 12576457·Clin Cancer Res·2003
8-other
Crystal structures of human GAR Tfase at low and high pH and with substrate beta-GAR.
PMID 12450384·Biochemistry·2002
4-observational
The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate channeling.
PMID 11948179·J Biol Chem·2002
8-other
10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway.
PMID 12057663·Bioorg Med Chem·2002
8-other
Structural insights into the avian AICAR transformylase mechanism.
PMID 12501179·Biochemistry·2002
7-preclinical
Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.
PMID 11323713·Nat Struct Biol·2001
7-preclinical
Human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase. A bifunctional protein requiring dimerization for transformylase activity but not for cyclohydrolase activity.
PMID 11096114·J Biol Chem·2001
8-other
Dihydrofolate reductase from Kaposi's sarcoma-associated herpesvirus.
PMID 10683342·Virology·2000
4-observational
Crystallization and preliminary crystallographic investigations of avian 5-aminoimidazole-4-carboxamide ribonucleotide transformylase-inosine monophosphate cyclohydrolase expressed in Escherichia coli.
PMID 10944351·Acta Crystallogr D Biol Crystallogr·2000
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 3 locations total
- Address
- 2550 W Clinton Ave Bldg W
Fresno, CA 93705 - Phone
- (808) 721-7278
Quick Facts
- NPI
- 1790789600
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 3
- Publications
- 13
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