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ROXANA LUPU, MD
MD
Hospitalist Physician
NPI: 1801059936IndividualAccepts Medicare
Specialties, Licenses & Credentials
Internal Medicine Physician
Internal Medicine
Code: 207R00000X
8361(SD)003827(NY)
Hospitalist PhysicianPrimary
Hospitalist
Code: 208M00000X
8361(SD)
CMS Specialties
PrimaryHOSPITALIST
Education
OTHER
Class of 2003
Research & Publications (20)
Cyr61 downmodulation potentiates the anticancer effects of zoledronic acid in androgen-independent prostate cancer cells.
PMID 19530242·Int J Cancer·2009
8-other
Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells.
PMID 19467222·Biochem Biophys Res Commun·2009
8-other
Giacomo Castelvetro's salads. Anti-HER2 oncogene nutraceuticals since the 17th century?
PMID 18208790·Clin Transl Oncol·2008
8-other
Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells.
PMID 18211286·Cell Prolif·2008
7-preclinical
Plasminogen-induced aggregation of PANC-1 cells requires conversion to plasmin and is inhibited by endogenous plasminogen activator inhibitor-1.
PMID 18366077·J Cell Physiol·2008
7-preclinical
An easy, rapid and objective mathematical method to identify fatty acid synthase (oncogenic antigen-519) modulators with potential anticancer value.
PMID 18411195·Clin Transl Oncol·2008
8-other
Transphosphorylation of kinase-dead HER3 and breast cancer progression: a new standpoint or an old concept revisited?
PMID 17983482·Breast Cancer Res·2007
8-other
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis.
PMID 17882277·Nat Rev Cancer·2007
6-review
Up-regulation of alphavbeta3 integrin expression is a novel molecular response to chemotherapy-induced cell damage in a heregulin-dependent manner.
PMID 17999741·Differentiation·2007
8-other
Targeting human epidermal growth factor receptor 2: it is time to kill kinase death human epidermal growth factor receptor 3.
PMID 17557968·J Clin Oncol·2007
8-other
DNA topoisomerase IIalpha (TOP2A) inhibitors up-regulate fatty acid synthase gene expression in SK-Br3 breast cancer cells: in vitro evidence for a 'functional amplicon' involving FAS, Her-2/neu and TOP2A genes.
PMID 17089011·Int J Mol Med·2006
8-other
HER2 (erbB-2)-targeted effects of the omega-3 polyunsaturated fatty acid, alpha-linolenic acid (ALA; 18:3n-3), in breast cancer cells: the "fat features" of the "Mediterranean diet" as an "anti-HER2 cocktail".
PMID 17134970·Clin Transl Oncol·2006
8-other
Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?
PMID 17168665·Curr Pharm Biotechnol·2006
6-review
Trastuzumab in combination with heregulin-activated Her-2 (erbB-2) triggers a receptor-enhanced chemosensitivity effect in the absence of Her-2 overexpression.
PMID 16847284·J Clin Oncol·2006
8-other
Targeting fatty acid synthase in breast and endometrial cancer: An alternative to selective estrogen receptor modulators?
PMID 16809439·Endocrinology·2006
4-observational
A genomic explanation connecting "Mediterranean diet", olive oil and cancer: oleic acid, the main monounsaturated fatty acid of olive oil, induces formation of inhibitory "PEA3 transcription factor-PEA3 DNA binding site" complexes at the Her-2/neu (erbB-2) oncogene promoter in breast, ovarian and stomach cancer cells.
PMID 16406575·Eur J Cancer·2006
8-other
A bidirectional "alpha(v)beta(3) integrin-ERK1/ERK2 MAPK" connection regulates the proliferation of breast cancer cells.
PMID 16705745·Mol Carcinog·2006
8-other
Oncogenic properties of the endogenous fatty acid metabolism: molecular pathology of fatty acid synthase in cancer cells.
PMID 16778562·Curr Opin Clin Nutr Metab Care·2006
6-review
Mediterranean dietary traditions for the molecular treatment of human cancer: anti-oncogenic actions of the main olive oil's monounsaturated fatty acid oleic acid (18:1n-9).
PMID 17168666·Curr Pharm Biotechnol·2006
6-review
Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene.
PMID 16264182·J Natl Cancer Inst·2005
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1305 W 18TH ST
SIOUX FALLS, SD 57105 - Phone
- (605) 328-4973
Quick Facts
- NPI
- 1801059936
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Accepted
- Specialties
- 3
- Locations
- 1
- Years in Practice
- 23
- Publications
- 20
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