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THOMAS APPLEBY, M.D.
M.D.
Vascular Surgery Physician
NPI: 1801985007IndividualAccepts Medicare
Specialties, Licenses & Credentials
Education
MEDICAL UNIVERSITY OF SOUTH CAROLINA COLLEGE OF MEDICINE
Class of 1985
Research & Publications (12)
Structure of human uridine-cytidine kinase 2 determined by SIRAS using a rotating-anode X-ray generator and a single samarium derivative.
PMID 15735337·Acta Crystallogr D Biol Crystallogr·2005
8-other
Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: convergence of structure-based drug design and X-ray crystallographic study.
PMID 17276060·Bioorg Med Chem Lett·2007
8-other
Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase.
PMID 17251021·Bioorg Med Chem Lett·2007
8-other
Isothiazoles as active-site inhibitors of HCV NS5B polymerase.
PMID 17049853·Bioorg Med Chem Lett·2007
8-other
Novel thiazolones as HCV NS5B polymerase allosteric inhibitors: Further designs, SAR, and X-ray complex structure.
PMID 17049849·Bioorg Med Chem Lett·2007
8-other
Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors.
PMID 16934458·Bioorg Med Chem Lett·2006
7-preclinical
Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors.
PMID 16934455·Bioorg Med Chem Lett·2006
4-observational
Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer.
PMID 15596823·J Virol·2005
8-other
Hepatitis C virus therapies: current treatments, targets and future perspectives.
PMID 12790512·Antivir Chem Chemother·2003
6-review
Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus.
PMID 11489901·J Biol Chem·2001
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
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Contact & Hours
- Address
- 2575 ELMS CENTER RD STE 200
NORTH CHARLESTON, SC 29406 - Phone
- (843) 724-1950
Quick Facts
- NPI
- 1801985007
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 41
- Publications
- 12
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