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JOHN BREAM, M.D.
M.D.
Family Medicine Physician
NPI: 1811124266IndividualAccepts Medicare
Specialties, Licenses & Credentials
Emergency Medicine Physician
Emergency Medicine
Code: 207P00000X
201002059(NC)
Family Medicine PhysicianPrimary
Family Medicine
Code: 207Q00000X
2010-02059(NC)
Education
BRODY SCHOOL OF MEDICINE AT EAST CAROLINA UNIVERSITY
Class of 2009
Research & Publications (20)
A distal region in the interferon-gamma gene is a site of epigenetic remodeling and transcriptional regulation by interleukin-2.
PMID 15271977·J Biol Chem·2004
8-other
IL-4 synergistically enhances both IL-2- and IL-12-induced IFN-gamma expression in murine NK cells.
PMID 12637316·Blood·2003
7-preclinical
A single nucleotide polymorphism in the proximal IFN-gamma promoter alters control of gene transcription.
PMID 12070781·Genes Immun·2002
7-preclinical
Microbial translocation, the innate cytokine response, and HIV-1 disease progression in Africa.
PMID 19357303·Proc Natl Acad Sci U S A·2009
8-other
Mitochondrial DNA haplogroups influence lipoatrophy after highly active antiretroviral therapy.
PMID 19339895·J Acquir Immune Defic Syndr·2009
8-other
Long-term serologic responses to the Pneumocystis jirovecii major surface glycoprotein in HIV-positive individuals with and without P. jirovecii infection.
PMID 19301979·J Infect Dis·2009
8-other
Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling.
PMID 18542053·Oncogene·2008
7-preclinical
Stat4-dependent, T-bet-independent regulation of IL-10 in NK cells.
PMID 18401353·Genes Immun·2008
7-preclinical
Preclinical evaluation of targeting the Nrf2 pathway by triterpenoids (CDDO-Im and CDDO-Me) for protection from LPS-induced inflammatory response and reactive oxygen species in human peripheral blood mononuclear cells and neutrophils.
PMID 17822364·Antioxid Redox Signal·2007
8-other
FcgammaRIIa genotype predicts progression of HIV infection.
PMID 18025239·J Immunol·2007
4-observational
IFN-gamma: recent advances in understanding regulation of expression, biological functions, and clinical applications.
PMID 17969445·Curr Top Microbiol Immunol·2007
6-review
IL-4 induces a wide-spectrum intracellular signaling cascade in CD8+ T cells.
PMID 17200144·J Leukoc Biol·2007
7-preclinical
An IFNG SNP with an estrogen-like response element selectively enhances promoter expression in peripheral but not lamina propria T cells.
PMID 16724074·Genes Immun·2006
8-other
T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription.
PMID 16520391·J Exp Med·2006
7-preclinical
Opposing roles of NF-kappaB family members in the regulation of NK cell proliferation and production of IFN-gamma.
PMID 16481345·Int Immunol·2006
7-preclinical
Stat5a/b are essential for normal lymphoid development and differentiation.
PMID 16418296·Proc Natl Acad Sci U S A·2006
7-preclinical
Synergistic effect of IL-2, IL-12, and IL-18 on thymocyte apoptosis and Th1/Th2 cytokine expression.
PMID 15728489·J Immunol·2005
4-observational
Analysis of the 5q31-q33 locus shows an association between IL13-1055C/T IL-13-591A/G polymorphisms and Schistosoma haematobium infections.
PMID 15879126·J Immunol·2005
7-preclinical
Enhancer role of STAT5 in CD2 activation of IFN-gamma gene expression.
PMID 15528362·J Immunol·2004
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 3 locations total
- Address
- 314 W Queen St
Edenton, NC 27932 - Phone
- (252) 482-3350
Quick Facts
- NPI
- 1811124266
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 2
- Locations
- 3
- Years in Practice
- 17
- Publications
- 20
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