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WILLIAM LEMAIRE, MD
MD
Obstetrics Physician
NPI: 1811198252Individual
Specialties, Licenses & Credentials
Obstetrics PhysicianPrimary
Obstetrics & Gynecology — Obstetrics
Code: 207VX0000X
12658(FL)
Research & Publications (19)
Positive allosteric interaction of structurally diverse T-type calcium channel antagonists.
PMID 19582593·Cell Biochem Biophys·2009
7-preclinical
Discovery of a potent, CNS-penetrant orexin receptor antagonist based on an n,n-disubstituted-1,4-diazepane scaffold that promotes sleep in rats.
PMID 19418500·ChemMedChem·2009
7-preclinical
Discovery of GlyT1 inhibitors with improved pharmacokinetic properties.
PMID 19181525·Bioorg Med Chem Lett·2009
4-observational
Discovery of N-{[1-(propylsulfonyl)-4-pyridin-2-ylpiperidin-4-yl]methyl}benzamides as novel, selective and potent GlyT1 inhibitors.
PMID 19179073·Bioorg Med Chem Lett·2009
4-observational
A novel radioligand for glycine transporter 1: characterization and use in autoradiographic and in vivo brain occupancy studies.
PMID 18355687·Nucl Med Biol·2008
7-preclinical
Proline bis-amides as potent dual orexin receptor antagonists.
PMID 18207395·Bioorg Med Chem Lett·2008
7-preclinical
Alpha-hydroxy amides as a novel class of bradykinin B1 selective antagonists.
PMID 18061443·Bioorg Med Chem Lett·2008
7-preclinical
Challenges in the development of mGluR5 positive allosteric modulators: the discovery of CPPHA.
PMID 17210250·Bioorg Med Chem Lett·2007
7-preclinical
Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamides.
PMID 16987662·Bioorg Med Chem Lett·2006
7-preclinical
Design, synthesis, and in vivo efficacy of glycine transporter-1 (GlyT1) inhibitors derived from a series of [4-phenyl-1-(propylsulfonyl)piperidin-4-yl]methyl benzamides.
PMID 16902933·ChemMedChem·2006
7-preclinical
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models.
PMID 15608073·J Pharmacol Exp Ther·2005
4-observational
Discovery of positive allosteric modulators for the metabotropic glutamate receptor subtype 5 from a series of N-(1,3-diphenyl-1H- pyrazol-5-yl)benzamides that potentiate receptor function in vivo.
PMID 15537338·J Med Chem·2004
7-preclinical
A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain.
PMID 14747613·J Pharmacol Exp Ther·2004
7-preclinical
Difference in mGluR5 interaction between positive allosteric modulators from two structural classes.
PMID 14684495·Ann N Y Acad Sci·2003
7-preclinical
Development of a scintillation proximity assay for analysis of Na+/Cl- -dependent neurotransmitter transporter activity.
PMID 12963052·Anal Biochem·2003
8-other
The glycine transporter type 1 inhibitor N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior.
PMID 12930797·J Neurosci·2003
7-preclinical
A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.
PMID 12920211·Mol Pharmacol·2003
7-preclinical
A nonpeptide oxytocin receptor antagonist radioligand highly selective for human receptors.
PMID 12176104·Eur J Pharmacol·2002
4-observational
Placenta percreta with spontaneous rupture of an unscarred uterus in the second trimester.
PMID 11704207·Obstet Gynecol·2001
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 650 CORAL WAY, APT #305
CORAL GABLES, FL 33134 - Phone
- (305) 567-2500
Quick Facts
- NPI
- 1811198252
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 19
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