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FRANCES HIGH, M.D., PH.D.
M.D., PH.D.
Clinical Genetics (M.D.) Physician
NPI: 1831325224IndividualAccepts Medicare
Specialties, Licenses & Credentials
Clinical Genetics (M.D.) PhysicianPrimary
Medical Genetics — Clinical Genetics (M.D.)
Code: 207SG0201X
255675(MA)
Pediatrics Physician
Pediatrics
Code: 208000000X
255675(MA)
CMS Specialties
PrimaryPEDIATRIC MEDICINE
Additional
MEDICAL GENETICS AND GENOMICS
Education
PERELMAN SCHOOL OF MED AT THE UNIVERSITY OF PENNSYLVANIA
Class of 2009
Research & Publications (16)
Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development.
PMID 19509466·J Clin Invest·2009
7-preclinical
Phase I dose-escalation study of the thioxanthone SR271425 administered intravenously once every 3 weeks in patients with advanced malignancies.
PMID 18449472·Invest New Drugs·2008
3-trial
Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development.
PMID 18245384·Proc Natl Acad Sci U S A·2008
7-preclinical
The multifaceted role of Notch in cardiac development and disease.
PMID 18071321·Nat Rev Genet·2008
6-review
Signalling pathways regulating cardiac neural crest migration and differentiation.
PMID 18300420·Novartis Found Symp·2007
7-preclinical
An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.
PMID 17273555·J Clin Invest·2007
7-preclinical
N-cadherin is required for neural crest remodeling of the cardiac outflow tract.
PMID 17014840·Dev Biol·2006
7-preclinical
Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives.
PMID 15882581·Dev Biol·2005
7-preclinical
Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation.
PMID 15484194·Eur J Immunol·2004
7-preclinical
Cutting Edge: Innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter.
PMID 15265878·J Immunol·2004
4-observational
Gene silencing quantitatively controls the function of a developmental trans-activator.
PMID 12150909·Mol Cell·2002
7-preclinical
Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction.
PMID 12055627·Nat Immunol·2002
7-preclinical
Cell cycle controlling the silencing and functioning of mammalian activators.
PMID 11696328·Curr Biol·2001
8-other
Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells.
PMID 11581312·J Exp Med·2001
7-preclinical
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.
PMID 11397944·Science·2001
7-preclinical
The RGG domain in hnRNP A2 affects subcellular localization.
PMID 10772824·Exp Cell Res·2000
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 55 FRUIT ST
BOSTON, MA 02114 - Phone
- (617) 355-8241
Quick Facts
- NPI
- 1831325224
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Accepted
- Specialties
- 2
- Locations
- 1
- Years in Practice
- 17
- Publications
- 16
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