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WILLIAM SKACH, MD
MD
Hematology & Oncology Physician
NPI: 1841206430Individual
Specialties, Licenses & Credentials
Hematology & Oncology PhysicianPrimary
Internal Medicine — Hematology & Oncology
Code: 207RH0003X
MD15063(OR)
Research & Publications (20)
The expanding role of the ER translocon in membrane protein folding.
PMID 18166647·J Cell Biol·2007
6-review
Defects in processing and trafficking of the cystic fibrosis transmembrane conductance regulator.
PMID 10720935·Kidney Int·2000
6-review
Sequence-specific retention and regulated integration of a nascent membrane protein by the endoplasmic reticulum Sec61 translocon.
PMID 19019984·Mol Biol Cell·2009
8-other
Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.
PMID 18480044·J Biol Chem·2008
8-other
Aquaporin-4 dynamics in orthogonal arrays in live cells visualized by quantum dot single particle tracking.
PMID 18495865·Mol Biol Cell·2008
7-preclinical
A novel tripartite motif involved in aquaporin topogenesis, monomer folding and tetramerization.
PMID 17632520·Nat Struct Mol Biol·2007
8-other
Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system.
PMID 17540174·Cell·2007
7-preclinical
Global organization and function of mammalian cytosolic proteasome pools: Implications for PA28 and 19S regulatory complexes.
PMID 16987959·Mol Biol Cell·2006
7-preclinical
p97 functions as an auxiliary factor to facilitate TM domain extraction during CFTR ER-associated degradation.
PMID 16977321·EMBO J·2006
7-preclinical
Molecular mechanisms of aquaporin biogenesis by the endoplasmic reticulum Sec61 translocon.
PMID 16782047·Biochim Biophys Acta·2006
6-review
Uncoupling proteasome peptidase and ATPase activities results in cytosolic release of an ER polytopic protein.
PMID 16390870·J Cell Sci·2006
7-preclinical
Aberrant folding of a mutant Stat5b causes growth hormone insensitivity and proteasomal dysfunction.
PMID 16303763·J Biol Chem·2006
7-preclinical
An energy-dependent maturation step is required for release of the cystic fibrosis transmembrane conductance regulator from early endoplasmic reticulum biosynthetic machinery.
PMID 16166089·J Biol Chem·2005
7-preclinical
Sequential triage of transmembrane segments by Sec61alpha during biogenesis of a native multispanning membrane protein.
PMID 16186821·Nat Struct Mol Biol·2005
7-preclinical
The cotranslational contacts between ribosome-bound nascent polypeptides and the subunits of the hetero-oligomeric chaperonin TRiC probed by photocross-linking.
PMID 15929940·J Biol Chem·2005
8-other
Reticulocyte lysate as a model system to study endoplasmic reticulum membrane protein degradation.
PMID 15917633·Methods Mol Biol·2005
7-preclinical
Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.
PMID 15835887·Biochemistry·2005
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 3181 SW SAM JACKSON PARK RD
PORTLAND, OR 97239 - Phone
- (503) 494-7322
Quick Facts
- NPI
- 1841206430
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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