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LAKSHMI NARASIMHAN, MD
MD
Specialist
NPI: 1841298619IndividualAccepts Medicare
Specialties, Licenses & Credentials
SpecialistPrimary
Specialist
Code: 174400000X
9500674(NC)
Education
OTHER
Class of 1979
Research & Publications (18)
Discovery of antibacterial biotin carboxylase inhibitors by virtual screening and fragment-based approaches.
PMID 19413326·ACS Chem Biol·2009
8-other
Exploration of 4,4-disubstituted pyrrolidine-1,2-dicarboxamides as potent, orally active Factor Xa inhibitors with extended duration of action.
PMID 19231206·Bioorg Med Chem·2009
8-other
A class of selective antibacterials derived from a protein kinase inhibitor pharmacophore.
PMID 19164768·Proc Natl Acad Sci U S A·2009
8-other
Adsorption into the MFI zeolite of aromatic molecule of biological relevance. Investigations by Monte Carlo simulations.
PMID 19130100·J Mol Model·2009
8-other
Discovery and SAR of benzyl phenyl ethers as inhibitors of bacterial phenylalanyl-tRNA synthetase.
PMID 19121937·Bioorg Med Chem Lett·2009
8-other
Structure of a small-molecule inhibitor complexed with GlmU from Haemophilus influenzae reveals an allosteric binding site.
PMID 18218712·Protein Sci·2008
8-other
Rational protein engineering in action: the first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus.
PMID 18086534·J Struct Biol·2008
8-other
The discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an orally efficacious factor Xa inhibitor.
PMID 17683371·Chem Biol Drug Des·2007
7-preclinical
Structure-based drug design of pyrrolidine-1, 2-dicarboxamides as a novel series of orally bioavailable factor Xa inhibitors.
PMID 17581239·Chem Biol Drug Des·2007
7-preclinical
The discovery of glycine and related amino acid-based factor Xa inhibitors.
PMID 16529937·Bioorg Med Chem·2006
8-other
The discovery of fluoropyridine-based inhibitors of the factor VIIa/TF complex--Part 2.
PMID 16289811·Bioorg Med Chem Lett·2006
8-other
The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex.
PMID 16125385·Bioorg Med Chem Lett·2005
8-other
Co-crystal structure and inhibition of factor Xa by PD0313052 identifies structurally stabilized active site residues of factor Xa and prothrombinase.
PMID 15981994·Biochemistry·2005
8-other
Design, synthesis, and biological activity of potent and selective inhibitors of blood coagulation factor Xa.
PMID 15267248·J Med Chem·2004
7-preclinical
A novel database of disulfide patterns and its application to the discovery of distantly related homologs.
PMID 14698301·J Mol Biol·2004
7-preclinical
Correlation of breath ammonia with blood urea nitrogen and creatinine during hemodialysis.
PMID 11296293·Proc Natl Acad Sci U S A·2001
8-other
Rational design, synthesis, and biological activity of benzoxazinones as novel factor Xa inhibitors.
PMID 11063603·J Med Chem·2000
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 264 MEMORIAL DR
JACKSONVILLE, NC 28546 - Phone
- (910) 455-7001
Quick Facts
- NPI
- 1841298619
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 47
- Publications
- 18
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