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JOHN MANFREDI, MD
MD
Orthopaedic Surgery Physician
NPI: 1841343027IndividualAccepts Medicare
Specialties, Licenses & Credentials
Orthopaedic Surgery PhysicianPrimary
Orthopaedic Surgery
Code: 207X00000X
58899(GA)
CMS Specialties
PrimaryORTHOPEDIC SURGERY
Education
JEFFERSON MEDICAL COLLEGE OF THOMAS JEFFERSON UNIVERSITY
Class of 2001
Research & Publications (20)
Insights from a novel p53 isoform in zebrafish want to reel us in, but will we take the bait?
PMID 19204113·Genes Dev·2009
7-preclinical
Inappropriate activation of cyclin-dependent kinases by the phosphatase Cdc25b results in premature mitotic entry and triggers a p53-dependent checkpoint.
PMID 19136558·J Biol Chem·2009
8-other
Cellular senescence and organismal ageing in the absence of p21(CIP1/WAF1) in ku80(-/-) mice.
PMID 19079133·EMBO Rep·2009
7-preclinical
Differentiating junctional tachycardia and atrioventricular node re-entry tachycardia based on response to atrial extrastimulus pacing.
PMID 19007691·J Am Coll Cardiol·2008
4-observational
Overexpression of the dual specificity phosphatase, Cdc25C, confers sensitivity on tumor cells to doxorubicin-induced cell death.
PMID 19074854·Mol Cancer Ther·2008
8-other
Mdm2 plays a positive role as an effector of p53-dependent responses.
PMID 17786043·Cell Cycle·2007
7-preclinical
Left ventricle remodelling by double-patch sandwich technique.
PMID 17266754·J Cardiothorac Surg·2007
8-other
Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest.
PMID 17371838·Mol Cell Biol·2007
7-preclinical
The dual specificity phosphatase Cdc25B, but not the closely related Cdc25C, is capable of inhibiting cellular proliferation in a manner dependent upon its catalytic activity.
PMID 17591782·J Biol Chem·2007
8-other
The dual specificity phosphatase Cdc25C is a direct target for transcriptional repression by the tumor suppressor p53.
PMID 16582636·Cell Cycle·2006
6-review
Gene-specific mechanisms of p53 transcriptional control and prospects for cancer therapy.
PMID 16676359·J Cell Biochem·2006
6-review
Disruption of G1-phase phospholipid turnover by inhibition of Ca2+-independent phospholipase A2 induces a p53-dependent cell-cycle arrest in G1 phase.
PMID 16492706·J Cell Sci·2006
8-other
The p53 tumor suppressor participates in multiple cell cycle checkpoints.
PMID 16741928·J Cell Physiol·2006
6-review
Target structure-based discovery of small molecules that block human p53 and CREB binding protein association.
PMID 16426974·Chem Biol·2006
8-other
The BICIRCUIT system: innovative perfusional options for surgical treatment of the thoracic aorta.
PMID 15680858·Ann Thorac Surg·2005
3-trial
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 2 locations total
- Address
- 1000 COWLES CLINIC WAY # CY-200
GREENSBORO, GA 30642 - Phone
- (770) 292-6500
Quick Facts
- NPI
- 1841343027
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 2
- Years in Practice
- 25
- Publications
- 20
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