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STEPHEN PLYMATE, M.D.
M.D.
Endocrinology, Diabetes & Metabolism Physician
NPI: 1861503260Individual
Specialties, Licenses & Credentials
Endocrinology, Diabetes & Metabolism PhysicianPrimary
Internal Medicine — Endocrinology, Diabetes & Metabolism
Code: 207RE0101X
MD00018159(WA)
Research & Publications (20)
An antibody targeting the type I insulin-like growth factor receptor enhances the castration-induced response in androgen-dependent prostate cancer.
PMID 17975155·Clin Cancer Res·2007
7-preclinical
Androgen receptor (AR) expression in AR-negative prostate cancer cells results in differential effects of DHT and IGF-I on proliferation and AR activity between localized and metastatic tumors.
PMID 15368471·Prostate·2004
7-preclinical
Increased manganese superoxide dismutase (SOD-2) is part of the mechanism for prostate tumor suppression by Mac25/insulin-like growth factor binding-protein-related protein-1.
PMID 12592389·Oncogene·2003
7-preclinical
Insulin-like growth factor-I receptor blockade improves outcome in mouse model of lung injury.
PMID 19011156·Am J Respir Crit Care Med·2009
4-observational
Oxidative DNA damage in the prostate may predispose men to a higher risk of prostate cancer.
PMID 19252750·Transl Oncol·2009
8-other
An six-amino acid motif in the alpha3 domain of MICA is the cancer therapeutic target to inhibit shedding.
PMID 19615970·Biochem Biophys Res Commun·2009
8-other
Obstructing shedding of the immunostimulatory MHC class I chain-related gene B prevents tumor formation.
PMID 19147769·Clin Cancer Res·2009
7-preclinical
CCL5 secreted by senescent aged fibroblasts induces proliferation of prostate epithelial cells and expression of genes that modulate angiogenesis.
PMID 19360811·J Cell Physiol·2009
8-other
Tumor suppressor BRCA1 is expressed in prostate cancer and controls insulin-like growth factor I receptor (IGF-IR) gene transcription in an androgen receptor-dependent manner.
PMID 19223505·Clin Cancer Res·2009
4-observational
Extracellular influences on tumour angiogenesis in the aged host.
PMID 18182993·Br J Cancer·2008
6-review
Effect of exercise on serum sex hormones in men: a 12-month randomized clinical trial.
PMID 18202581·Med Sci Sports Exerc·2008
2-rct
Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-beta in memory-impaired older adults.
PMID 18430999·J Alzheimers Dis·2008
8-other
Insulin-like growth factor-i regulates Kruppel-like factor-6 gene expression in a p53-dependent manner.
PMID 18174288·Endocrinology·2008
8-other
Senescence-induced alterations of laminin chain expression modulate tumorigenicity of prostate cancer cells.
PMID 19048114·Neoplasia·2008
7-preclinical
Intranasal insulin improves cognition and modulates beta-amyloid in early AD.
PMID 17942819·Neurology·2008
2-rct
Regulation of global gene expression in the bone marrow microenvironment by androgen: androgen ablation increases insulin-like growth factor binding protein-5 expression.
PMID 17823924·Prostate·2007
7-preclinical
Comparison of the cytotoxicity of the nitroaromatic drug flutamide to its cyano analogue in the hepatocyte cell line TAMH: evidence for complex I inhibition and mitochondrial dysfunction using toxicogenomic screening.
PMID 17702527·Chem Res Toxicol·2007
4-observational
Muscle-specific overexpression of the type 1 IGF receptor results in myoblast-independent muscle hypertrophy via PI3K, and not calcineurin, signaling.
PMID 17940216·Am J Physiol Endocrinol Metab·2007
7-preclinical
The effects of aging on tumor growth and angiogenesis are tumor-cell dependent.
PMID 17131319·Int J Cancer·2007
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1660 S COLUMBIAN WAY
SEATTLE, WA 98108 - Phone
- (206) 762-1010
Quick Facts
- NPI
- 1861503260
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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