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TIMOTHY LOO, M.D.
M.D.
Internal Medicine Physician
NPI: 1871584813IndividualAccepts Medicare
Specialties, Licenses & Credentials
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
215918(MA)
Education
JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
Class of 1994
Research & Publications (20)
Schizosaccharomyces pombe Pak-related protein, Pak1p/Orb2p, phosphorylates myosin regulatory light chain to inhibit cytokinesis.
PMID 19029336·J Cell Biol·2008
8-other
Using secretion to solve a solubility problem: high-yield expression in Escherichia coli and purification of the bacterial glycoamidase PNGase F.
PMID 11812228·Protein Expr Purif·2002
8-other
Identification of residues in the drug translocation pathway of the human multidrug resistance P-glycoprotein by arginine mutagenesis.
PMID 19581304·J Biol Chem·2009
8-other
Rhodamine inhibitors of P-glycoprotein: an amide/thioamide "switch" for ATPase activity.
PMID 19402665·J Med Chem·2009
7-preclinical
Brain-derived neurotrophic factor (BDNF) has proliferative effects on neural stem cells through the truncated TRK-B receptor, MAP kinase, AKT, and STAT-3 signaling pathways.
PMID 19355925·Curr Neurovasc Res·2009
7-preclinical
Early prenatal diagnosis of semilobar holoprosencephaly combined with a dorsal cyst and no facial defect.
PMID 19126512·Taiwan J Obstet Gynecol·2008
5-case
Processing mutations disrupt interactions between the nucleotide binding and transmembrane domains of P-glycoprotein and the cystic fibrosis transmembrane conductance regulator (CFTR).
PMID 18708637·J Biol Chem·2008
8-other
Correctors promote folding of the CFTR in the endoplasmic reticulum.
PMID 18361776·Biochem J·2008
8-other
Day length and estradiol affect same-sex affiliative behavior in the female meadow vole.
PMID 18387611·Horm Behav·2008
7-preclinical
Arginines in the first transmembrane segment promote maturation of a P-glycoprotein processing mutant by hydrogen bond interactions with tyrosines in transmembrane segment 11.
PMID 18596043·J Biol Chem·2008
8-other
Atypical ovarian hyperstimulation syndrome with isolated pleural effusion but without ascites or hemoconcentration.
PMID 17638630·Taiwan J Obstet Gynecol·2007
5-case
Suppressor mutations in the transmembrane segments of P-glycoprotein promote maturation of processing mutants and disrupt a subset of drug-binding sites.
PMID 17848563·J Biol Chem·2007
8-other
Nucleotide binding, ATP hydrolysis, and mutation of the catalytic carboxylates of human P-glycoprotein cause distinct conformational changes in the transmembrane segments.
PMID 17636884·Biochemistry·2007
4-observational
Correctors promote maturation of cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by binding to the protein.
PMID 17911111·J Biol Chem·2007
8-other
Modulating the folding of P-glycoprotein and cystic fibrosis transmembrane conductance regulator truncation mutants with pharmacological chaperones.
PMID 17132688·Mol Pharmacol·2007
8-other
Additive effect of multiple pharmacological chaperones on maturation of CFTR processing mutants.
PMID 17535157·Biochem J·2007
7-preclinical
Chemical and pharmacological chaperones as new therapeutic agents.
PMID 17597553·Expert Rev Mol Med·2007
6-review
Transmembrane segment 7 of human P-glycoprotein forms part of the drug-binding pocket.
PMID 16813563·Biochem J·2006
8-other
Insertion of an arginine residue into the transmembrane segments corrects protein misfolding.
PMID 16926162·J Biol Chem·2006
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 330 BROOKLINE AVE, DEACONESS 311
BOSTON, MA 02215 - Phone
- (617) 667-9600
Quick Facts
- NPI
- 1871584813
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 32
- Publications
- 20
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