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DAVID THURSTON, MD
MD
Orthopaedic Surgery Physician
NPI: 1871933507Individual
Specialties, Licenses & Credentials
Orthopaedic Surgery PhysicianPrimary
Orthopaedic Surgery
Code: 207X00000X
10947(KS)
Research & Publications (20)
Observation of a dynamic equilibrium between DNA hairpin and duplex forms of covalent adducts of a minor groove binding agent.
PMID 19099077·Chem Commun (Camb)·2009
8-other
Biaryl polyamides as a new class of DNA quadruplex-binding ligands.
PMID 19568645·Chem Commun (Camb)·2009
8-other
Effect of microwave irradiation on covalent ligand-DNA interactions.
PMID 19436895·Chem Commun (Camb)·2009
8-other
ABCB1 genetic polymorphism influences the pharmacology of the new pyrrolobenzodiazepine derivative SJG-136.
PMID 17563765·Pharmacogenomics J·2008
4-observational
Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78.
PMID 18483319·Mol Cancer Ther·2008
7-preclinical
Fluorescent 7-diethylaminocoumarin pyrrolobenzodiazepine conjugates: synthesis, DNA interaction, cytotoxicity and differential cellular localization.
PMID 18280154·Bioorg Med Chem Lett·2008
8-other
Solution structure of a 2:1 C2-(2-naphthyl) pyrrolo[2,1-c][1,4]benzodiazepine DNA adduct: molecular basis for unexpectedly high DNA helix stabilization.
PMID 18925745·Biochemistry·2008
8-other
Are lateral electronic portal images adequate for accurate on-line daily targeting of the prostate? Results of a prospective study.
PMID 18262119·Med Dosim·2008
3-trial
Concomitant adsorption and desorption of organic vapor in dry and humid air streams using microwave and direct electrothermal swing adsorption.
PMID 19174910·Environ Sci Technol·2008
8-other
An assay combining high-performance liquid chromatography and mass spectrometry to measure DNA interstrand cross-linking efficiency in oligonucleotides of varying sequences.
PMID 18082123·Anal Biochem·2008
8-other
An asymmetric C8/C8'-tripyrrole-linked sequence-selective pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimer DNA interstrand cross-linking agent spanning 11 DNA base pairs.
PMID 18272367·Bioorg Med Chem Lett·2008
8-other
Interactions of pyrrolobenzodiazepine dimers and duplex DNA from methicillin-resistant Staphylococcus aureus.
PMID 17350809·Int J Antimicrob Agents·2007
8-other
Fludarabine-mediated suppression of the excision repair enzyme ERCC1 contributes to the cytotoxic synergy with the DNA minor groove crosslinking agent SJG-136 (NSC 694501) in chronic lymphocytic leukaemia cells.
PMID 17579621·Br J Cancer·2007
8-other
Synthesis of a novel C2-aryl pyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione library: effect of C2-aryl substitution on cytotoxicity and non-covalent DNA binding.
PMID 17317191·Bioorg Med Chem·2007
8-other
Preclinical pharmacology of the pyrrolobenzodiazepine (PBD) monomer DRH-417 (NSC 709119).
PMID 17309854·J Chemother·2007
7-preclinical
Steady-state and dynamic desorption of organic vapor from activated carbon with electrothermal swing adsorption.
PMID 17711224·Environ Sci Technol·2007
8-other
Phase III trial of intraperitoneal therapy with yttrium-90-labeled HMFG1 murine monoclonal antibody in patients with epithelial ovarian cancer after a surgically defined complete remission.
PMID 16446329·J Clin Oncol·2006
3-trial
Time-dependent cytotoxicity induced by SJG-136 (NSC 694501): influence of the rate of interstrand cross-link formation on DNA damage signaling.
PMID 16818520·Mol Cancer Ther·2006
8-other
Design, synthesis, and biophysical and biological evaluation of a series of pyrrolobenzodiazepine-poly(N-methylpyrrole) conjugates.
PMID 16942018·J Med Chem·2006
8-other
Marine with malaria on terminal leave after deployments to Iraq and Liberia.
PMID 17256676·Mil Med·2006
5-case
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 5120 REDBUD LANE
TOPEKA, KS 66606 - Phone
- (785) 272-9034
Quick Facts
- NPI
- 1871933507
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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