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THI LOO, PHARMD
PHARMD
Ambulatory Care Pharmacist
NPI: 1881314425Individual
Specialties, Licenses & Credentials
Ambulatory Care PharmacistPrimary
Pharmacist — Ambulatory Care
Code: 1835P2201X
77706(CA)
Research & Publications (20)
Identification of residues in the drug translocation pathway of the human multidrug resistance P-glycoprotein by arginine mutagenesis.
PMID 19581304·J Biol Chem·2009
8-other
Arginines in the first transmembrane segment promote maturation of a P-glycoprotein processing mutant by hydrogen bond interactions with tyrosines in transmembrane segment 11.
PMID 18596043·J Biol Chem·2008
8-other
Processing mutations disrupt interactions between the nucleotide binding and transmembrane domains of P-glycoprotein and the cystic fibrosis transmembrane conductance regulator (CFTR).
PMID 18708637·J Biol Chem·2008
8-other
Correctors promote folding of the CFTR in the endoplasmic reticulum.
PMID 18361776·Biochem J·2008
8-other
Suppressor mutations in the transmembrane segments of P-glycoprotein promote maturation of processing mutants and disrupt a subset of drug-binding sites.
PMID 17848563·J Biol Chem·2007
8-other
Nucleotide binding, ATP hydrolysis, and mutation of the catalytic carboxylates of human P-glycoprotein cause distinct conformational changes in the transmembrane segments.
PMID 17636884·Biochemistry·2007
4-observational
Correctors promote maturation of cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by binding to the protein.
PMID 17911111·J Biol Chem·2007
8-other
Chemical and pharmacological chaperones as new therapeutic agents.
PMID 17597553·Expert Rev Mol Med·2007
6-review
Insertion of an arginine residue into the transmembrane segments corrects protein misfolding.
PMID 16926162·J Biol Chem·2006
8-other
Using a cysteine-less mutant to provide insight into the structure and mechanism of CFTR.
PMID 16497707·J Physiol·2006
7-preclinical
Transmembrane segment 7 of human P-glycoprotein forms part of the drug-binding pocket.
PMID 16813563·Biochem J·2006
8-other
The chemical chaperone CFcor-325 repairs folding defects in the transmembrane domains of CFTR-processing mutants.
PMID 16417523·Biochem J·2006
7-preclinical
Transmembrane segment 1 of human P-glycoprotein contributes to the drug-binding pocket.
PMID 16492138·Biochem J·2006
7-preclinical
Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux.
PMID 16456713·J Membr Biol·2005
6-review
The dileucine motif at the COOH terminus of human multidrug resistance P-glycoprotein is important for folding but not activity.
PMID 15542593·J Biol Chem·2005
7-preclinical
Do drug substrates enter the common drug-binding pocket of P-glycoprotein through "gates"?
PMID 15737603·Biochem Biophys Res Commun·2005
7-preclinical
ATP hydrolysis promotes interactions between the extracellular ends of transmembrane segments 1 and 11 of human multidrug resistance P-glycoprotein.
PMID 16042402·Biochemistry·2005
8-other
Endometrioma undergoing laparoscopic ovarian cystectomy: its influence on the outcome of in vitro fertilization and embryo transfer (IVF-ET).
PMID 16247714·J Assist Reprod Genet·2005
8-other
Rescue of folding defects in ABC transporters using pharmacological chaperones.
PMID 16691490·J Bioenerg Biomembr·2005
6-review
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1200 EL CAMINO REAL
SOUTH SAN FRANCISCO, CA 94080 - Phone
- (650) 742-2000
Quick Facts
- NPI
- 1881314425
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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