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SARAFINA MUSTO, DO
DO
Pediatrics Physician
NPI: 1881343754Individual
Specialties, Licenses & Credentials
Pediatrics PhysicianPrimary
Pediatrics
Code: 208000000X
OS21888(FL)
Research & Publications (10)
Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of beta-tubulin (Asp26Glu) and less stable microtubules.
PMID 16505100·Mol Cancer Ther·2006
7-preclinical
Hybrids of the hemiasterlin analogue taltobulin and the dolastatins are potent antimicrotubule agents.
PMID 16351096·J Am Chem Soc·2005
8-other
2-(Quinazolin-4-ylamino)-[1,4]benzoquinones as covalent-binding, irreversible inhibitors of the kinase domain of vascular endothelial growth factor receptor-2.
PMID 16302797·J Med Chem·2005
7-preclinical
Two photoaffinity analogues of the tripeptide, hemiasterlin, exclusively label alpha-tubulin.
PMID 15865430·Biochemistry·2005
7-preclinical
Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulin.
PMID 15486199·Mol Cancer Ther·2004
7-preclinical
Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segment.
PMID 15454219·Bioorg Med Chem Lett·2004
7-preclinical
Synthesis and biological activity of analogues of the antimicrotubule agent N,beta,beta-trimethyl-L-phenylalanyl-N(1)-[(1S,2E)-3-carboxy-1-isopropylbut-2-enyl]- N(1),3-dimethyl-L-valinamide (HTI-286).
PMID 15341492·J Med Chem·2004
7-preclinical
MAC-321, a novel taxane with greater efficacy than paclitaxel and docetaxel in vitro and in vivo.
PMID 14555706·Mol Cancer Ther·2003
4-observational
HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
PMID 12702571·Cancer Res·2003
7-preclinical
Wants vs. needs. A case study in polypharmacy and drug advertising.
PMID 12420537·Adv Nurse Pract·2002
5-case
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1155 35TH LN STE 201A
VERO BEACH, FL 32960 - Phone
- (772) 562-5662
Quick Facts
- NPI
- 1881343754
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 10
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