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GOUTHAM NARLA, M.D PH.D
M.D PH.D
Internal Medicine Physician
NPI: 1881879138Individual
Specialties, Licenses & Credentials
Clinical Genetics (M.D.) Physician
Medical Genetics — Clinical Genetics (M.D.)
Code: 207SG0201X
PENDING(NY)
Internal Medicine PhysicianPrimary
Internal Medicine
Code: 207R00000X
35-120046(OH)
Research & Publications (20)
Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells.
PMID 19384952·Int J Cancer·2009
7-preclinical
KLF6-SV1 is a novel antiapoptotic protein that targets the BH3-only protein NOXA for degradation and whose inhibition extends survival in an ovarian cancer model.
PMID 19435908·Cancer Res·2009
7-preclinical
Targeted reduction of KLF6-SV1 restores chemotherapy sensitivity in resistant lung adenocarcinoma.
PMID 19328586·Lung Cancer·2009
7-preclinical
Functional role of the KLF6 tumour suppressor gene in gastric cancer.
PMID 19101139·Eur J Cancer·2009
7-preclinical
TGF-beta regulates the expression of transcription factor KLF6 and its splice variants and promotes co-operative transactivation of common target genes through a Smad3-Sp1-KLF6 interaction.
PMID 19076057·Biochem J·2009
7-preclinical
Increased alternative splicing of the KLF6 tumour suppressor gene correlates with prognosis and tumour grade in patients with pancreatic cancer.
PMID 18691883·Eur J Cancer·2008
8-other
KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.
PMID 18596922·J Clin Invest·2008
7-preclinical
The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease.
PMID 18515091·Gastroenterology·2008
8-other
Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma.
PMID 18471523·Gastroenterology·2008
4-observational
A functional role for KLF6-SV1 in lung adenocarcinoma prognosis and chemotherapy response.
PMID 18250346·Cancer Res·2008
8-other
Insulin-like growth factor-i regulates Kruppel-like factor-6 gene expression in a p53-dependent manner.
PMID 18174288·Endocrinology·2008
8-other
KLF6 allelic loss is associated with tumor recurrence and markedly decreased survival in head and neck squamous cell carcinoma.
PMID 17621627·Int J Cancer·2007
8-other
Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma.
PMID 17514651·Int J Cancer·2007
8-other
In vivo regulation of p21 by the Kruppel-like factor 6 tumor-suppressor gene in mouse liver and human hepatocellular carcinoma.
PMID 17297474·Oncogene·2007
7-preclinical
Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation.
PMID 17196295·J Hepatol·2007
8-other
Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination.
PMID 16778100·Clin Cancer Res·2006
8-other
E-cadherin is a novel transcriptional target of the KLF6 tumor suppressor.
PMID 16702959·Oncogene·2006
8-other
Sex steroids have differential effects on growth and gene expression in primary human prostatic epithelial cell cultures derived from the peripheral versus transition zones.
PMID 16123118·Carcinogenesis·2006
8-other
Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation.
PMID 16230382·Cancer Res·2005
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 11100 EUCLID AVE
CLEVELAND, OH 44106 - Phone
- (216) 844-8500
Quick Facts
- NPI
- 1881879138
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 1
- Publications
- 20
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