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NICOLLE DONATO, DMD
DMD
Dentist
NPI: 1891258950Individual
Specialties, Licenses & Credentials
DentistPrimary
Dentist
Code: 122300000X
22DI02803900(NJ)
Research & Publications (20)
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.
PMID 19363292·J Clin Invest·2009
7-preclinical
An inhibitor-resistant mutant of Hck protects CML cells against the antiproliferative and apoptotic effects of the broad-spectrum Src family kinase inhibitor A-419259.
PMID 18794796·Oncogene·2008
7-preclinical
Association between imatinib-resistant BCR-ABL mutation-negative leukemia and persistent activation of LYN kinase.
PMID 18577747·J Natl Cancer Inst·2008
7-preclinical
Transcriptional repression of c-Myb and GATA-2 is involved in the biologic effects of C/EBPalpha in p210BCR/ABL-expressing cells.
PMID 18550858·Blood·2008
8-other
Sequencing of subcloned PCR products facilitates earlier detection of BCR-ABL1(T315I) and other mutants compared to direct sequencing of the ABL1 kinase domain.
PMID 18305550·Leukemia·2008
8-other
Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells.
PMID 18235045·Blood·2008
8-other
Abrogation of signal transducer and activator of transcription 3 reactivation after Src kinase inhibition results in synergistic antitumor effects.
PMID 17634553·Clin Cancer Res·2007
8-other
Phase I clinical and pharmacodynamic evaluation of oral CI-1033 in patients with refractory cancer.
PMID 17505003·Clin Cancer Res·2007
3-trial
Degrasyn activates proteasomal-dependent degradation of c-Myc.
PMID 17440106·Cancer Res·2007
7-preclinical
Activation of a novel Bcr/Abl destruction pathway by WP1130 induces apoptosis of chronic myelogenous leukemia cells.
PMID 17202319·Blood·2007
7-preclinical
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias.
PMID 16775234·N Engl J Med·2006
3-trial
Leukemogenesis induced by wild-type and STI571-resistant BCR/ABL is potently suppressed by C/EBPalpha.
PMID 16670262·Blood·2006
7-preclinical
Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model.
PMID 16507911·Am J Pathol·2006
7-preclinical
Hyperthermia engages the intrinsic apoptotic pathway by enhancing upstream caspase activation to overcome apoptotic resistance in MCF-7 breast adenocarcinoma cells.
PMID 16440323·J Cell Biochem·2006
8-other
Adaphostin-induced oxidative stress overcomes BCR/ABL mutation-dependent and -independent imatinib resistance.
PMID 16291594·Blood·2006
8-other
Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells.
PMID 16203784·Clin Cancer Res·2005
8-other
Imatinib mesylate suppresses cytokine synthesis by activated CD4 T cells of patients with chronic myelogenous leukemia.
PMID 16151467·Leukemia·2005
8-other
Induction of heparin-binding EGF-like growth factor and activation of EGF receptor in imatinib mesylate-treated squamous carcinoma cells.
PMID 15887238·J Cell Physiol·2005
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 456 MIDDLESEX AVE
METUCHEN, NJ 08840 - Phone
- (732) 548-5008
Quick Facts
- NPI
- 1891258950
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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